The objective of this research is to study satiation effects of aroma-taste interactions in dairy based products.
Source
Brief title
Condition
- Other condition
Synonym
Health condition
factoren van invloed op eetgedrag
Research involving
Sponsors and support
Intervention
No registrations found.
Outcome measures
Primary outcome
Differences in appetite profile, thirst and reward feelings (VAS) between the
test products and placebo product.
Secondary outcome
n.a.
Background summary
Worldwide, the prevalence of overweight and associated co-morbidities, is
increasing significantly. Reducing food intake and increasing physical activity
would be the best solution against overweight. For many people however, this is
difficult to deal with. Food products that would inhibit appetite would
facilitate this a lot. A customer from NIZO food research recently developed a
specific aroma-taste combination which may evoke satiety.
Study objective
The objective of this research is to study satiation effects of aroma-taste
interactions in dairy based products.
Study design
In a double-blind, placebo-controlled, randomised cross-over study the effect
of specific dairy based products on appetite profile, thirst and reward
feelings will be investigated.
Each subject visits the test location seven times in the morning in an
overnight-fasted state, with visits separated by a time interval of one week,
and presentation of a different dairy based product during each session.
Subjects will consume one beverage (100kcal/250 mL) every 2 * hours for 3
hours, starting at 8.00 a.m. In total, 2 dairy based products will be consumed
during one test session. Subjects will consume a cereal bar (50 kcal) along
with the first serving.
Intervention
Each subject visits the test location seven times in the morning in an
overnight-fasted state, with visits separated by a time interval of one week,
and presentation of a different dairy based product during each session.
Treatment order is counterbalanced across both test days and subjects.
Subjects will consume one dairy based product (100 kcal/ 250 mL) every 2 *
hours for 3 hours, starting at 8.00 a.m. In total, 2 dairy based products will
be consumed during one test session. Subjects will consume a cereal bar (50
kcal) along with the first serving. Visual Analogue Scales (VAS) measurements
will be performed to record perceived appetite profile, thirst and reward
feelings just before and after consumption of test and placebo products with 10
minutes intervals. At the VAS rating just after consumption of the dairy based
products, subjects assess the palatability of the dairy based products using
VAS.
Study burden and risks
Placebo and test products are food grade. Products will be produced in the food
grade NIZO food research pilot plant. All ingredients in the test and placebo
dairy based products are suitable for human consumption and already commonly
used in commercial products.
The dairy based products are microbiologically safe. NIZO food research BV will
perform microbiological tests before the products will be presented to the
subjects.
Except for increased feelings of fullness and changes in motivational state
(reward feelings), no side effects are expected for test products or placebo
product. Besides, no invasive measurements will be performed. Therefore, the
burden for the subjects is minimal and the risks associated with participation
are negligible.
15-1, Kyobashi 1-chome, Chuo-ku
Tokyo 104-8315, Japan
JP
15-1, Kyobashi 1-chome, Chuo-ku
Tokyo 104-8315, Japan
JP
Listed location countries
Age
Inclusion criteria
- gender: women
- age: 20-40 years old
- BMI 18.5-24.9 kg m-2
- subjects are healthy and are not allergic to, nor do they have an aversion to, any of the ingredients used in test and placebo products (based on self-report)
- informed consent
Exclusion criteria
- Subjects with weight increases or decreases exceeding 5 kg during the past year
- Subjects indicating current health problems (based on self-report)
- Subjects using any prescribed medication (with the exception of contraception for longer than three months)
- Subjects using gastrointestinally active medication during last 3 months (Lactulose, Norit, Antacids, beta-blocker, anti-depressant)
- Subjects with GI-tract disease or past surgeries
- Subjects with allergies, intolerance or dislikes of the test and placebo products
- Pregnancy or lactating during the study, or in the year preceding the study
- Subjects currently smoking and being a not-smoker who quits smoking within last six months and reported use of any nicotine containing products in the six months preceding the study and during the study itself
- Subjects consuming more than 14 alcoholic drinks in a typical week
- Being not used to eating 3 meals a day
- Strenuous exercise >= 10 hours per week
- Subjects scoring >= 2 on SCOFF questionnaire (eating disorders)
- Subjects scoring >= 10 on the dietary restraint scale of TFEQ
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL37577.081.11 |