7242 results
Our proposed randomized controlled trial is the first making this head-to-head comparison in a *real life* primary care setting in the Netherlands. The primary research question is: does a 12-week combination therapy of open label varenicline and…
This study will learn us about the prevalence of asymptomatic urinary retention postpartum, as well as the natural course and complications.
To investigate if there are differences in serotonin transporters in the hypothalamus between subjects with hypopituitarism suspect for hypothalamic damage, subjects with hypopituitarism and no suspicion of hypothalamic damage and healthy age- and…
To determine whether increased calcium and phosphate intake (2005 group) resulted in improved Bone Mineral Content (BMC) and Bone Mineral Density (BMD) compared to the group with less calcium and phosphate intake (2004 group) at the age of 8-10…
Main objective: To evaluate the pain reduction in patients receiving Instanyl®Secondary objectives: To evaluate; the duration of pain reduction in patients receiving Instanyl®; the degree of adverse effects in patients receiving Instanyl®: whether…
Primary Objective: To investigate the association between the weight-loss-induced cellular stress response and the rate of weight regain. Secondary Objective: To investigate the difference in cellular stress response and weight regain after rapid…
The objectives of this study are:- to evaluate the potential of dalcetrapib to reduce cardiovascular morbidity and mortality in adult patients with stable coronary heart disease (CHD), CHD risk equivalents or at elevated risk for cardiovascular…
Primary Objective: To determine the prevalence of endo- and extranasal deformities, problems with nasal functioning and satisfaction with nasal appearance in patients with TCS.Secondary Objective: To adjust and improve the treatment of patients with…
To investigate differences in clinical outcome between patients with lytic spondylolisthesis and residual hernia surgery pain undergoing minimal invasive spinal fusion surgery. Beside this clinical outcome we investigate the radiological outcome of…
Collect data nationally to achieve a transparant view on the results of the patellofemoral prosthesis.
Extent the current instrument for assessing autism in deafblind individuals with profound intellectual disability by Hoevenaars-van den Boom et al. (2008; 2009) to a protocol with manual for assessing autism in people with visual impairments, less…
The objective of this study is to investigate whether thrombin generation is effected by different shear rates and different tissue factor concentrations in plasma, platelet rich plasma and whole blood. Thrombin generation in plasma with/without…
To evaluate the efficacy of Arnica om postoperative outcome after upper blepharoplasty.
To monitor the electric activity of the urinary bladder, and to localize the pacemaker, and the path of electric signal propagation of the detrusor muscle contractions.
In the current study we will re-examine the participants of the CODAM study in a second follow-up evaluation (12 yrs after baseline) in order to obtain further longitudinal information on the natural development of type 2 diabetes and cardiovascular…
Primary Objective: to compare the atrial contractility by means of echocardiography between patients receiving flecainide and vernakalant i.v. after conversion to sinus rhythmSecondary Objective(s): 2a. To compare the conversion rate of AF between…
The primary aim of this study is to investigate the efficacy of MBT-DH in comparison to MBT-IOP. A secondary aim is to explore the cost-effectiveness and matching potential of various baseline variables that might help treatment selection procedures…
The primary objective is to elucidate the question whether historic HBV viral load (in samples taken from 1989 * 1996 during pregnancy) is associated with the risk of HBV-related cirrhosis or mortality in a cohort of non-Asian individuals with…
Clinical evaluation of dried blood spot assay for the determination of tamoxifen and endoxifen levels
To determine the dose-limiting toxicities (DLTs) and maximum tolerated dose (MTD) of MK-8353 administered orally in combination with other agents to adult subjects with advanced tumors and to determine the recommended Phase 2 dose (RPTD) of MK-8353…