208 results
Primary objective: determine whether HAPTOS intervention results in earlier attainment (postnatal days) of full enteral feeding and/or full oral feeding (postmenstrual age) compared to standard care. Secondary objectives: To determine whether Haptos…
The aim of this study is to evaluate the AUC, disease status, presence of ADAbs and treatment burden when switching from IV to SC IFX maintenance treatment in a real-world cohort of IBD patients on IFX monotherapy and combination therapy.
1. To gain insights into care needs with regard to death wishes, death thoughts and suicidality of people requesting euthanasia due to psychological suffering;2. To gain insights into characteristics of death wishes, death thoughts and suicidality…
Primary objective:1) To determine the discriminating ability of the microvasculature between uteri with adenomyosis, myomas and no uterine disorders. Secondary Objectives: 2) To determine the discriminating ability of the microvasculature between…
Specific Aim 1) To identify the frequency and risk factors for PVA and its subtypes in ventilated children, with a specific focus on DC breaths. Hypothesis: PVA subtypes related to inadequate ventilator support (flow undershoot and premature cycling…
The primary objective of the study is to examine the effects of group SFT for an out-patient ED population, as assessed by change in both ED pathology as in core self-beliefs. Hypotheses:1. There will be a decrease in dysfunctional core self-beliefs…
The primary objective of this study is to investigate the local tolerability of isoniazid inhalation by wet nebulization at ascending dosages. Secondary objective is systemic pharmacokinetics of inhaled isoniazid compared to intravenous dose…
The primary objective is to evaluate if and to what extend replacing all meat products in an average Dutch diet with currently commercially available PBMAs affects the systolic blood pressure of middle aged men and women in a 2x8 week fully dietary…
We aim to confirm that Maastro endoluminal HDR contact brachytherapy boosting is feasible and may increase the chance of functional organ sparing of the rectum in patients with rectal cancer.
This study aims to assess the User experience, Usability and Safety perception of the HEROES exergame in a home environment for people with stroke. This study aims to identify the advantages and disadvantages of the current version of the HEROES of…
The major objective of this clinical investigation is to demonstrate safety and effectiveness of the ablation system (OMNYPULSE* Bi-Directional Catheter and TRUPULSE* Generator) when used for isolation of the atrial PVs in treatment of subjects with…
The primary objective is to execute a feasibility study of the ELFI Health lifestyle intervention for three months in people with prediabetes in primary care (based on HbA1c). The secondary objectives are assessing the impact of the ELFI health…
Primary objective: To compare the exposure of ETI in a group of pwCF with the highest decrease in sweat chlorid and the lowest decrease in sweat chloride as result of ETI therapy.
The aim of the study is to investigate whether SI-NETs can be visualized with indocyanine green (ICG) and near-infrared (NIR) fluorescence imaging (FLI).
In this project, pharmacotherapy will be used to target the molecular basis of memory consolidation in the acute trauma phase to prevent the intrusive aspects of traumatic memories from forming. An excellent candidate to pharmacologically manipulate…
Primary objectives:- To assess the differences in resting state EEG frequency spectrum analysis between patients with neurodegenerative and patients with non-neurological causes of MCI.* Power in microvolts squared of resting stage EEG for different…
To determine whether guided growth of the proximal femur decreases the risk of further hip migration and need for further surgery in cerebral palsy patients.
The main objective is to investigate whether the additional use of IVUS leads to an increase in net lumen gain (NLG) when compared with standard angiography-guided endovascular treatment as measured during control IVUS after six weeks. Secondary…
To evaluate the effect of transcutaneous electrical nerve stimulation (TENS) in patients with ANOCA on the change in the summary score of the Seattle Angina Questionnaire (SS SAQ) after 1 month treatment with TENS, compared to baseline.
To test whether tACS in a theta frequency enhances extinction of physiological stress responses to exposure to anxiety- or trauma-related stimuli or memories. Secondarily, to examine the influence of baseline neuroendocrinological response, baseline…