2263 results
Primary Objective: To assess the hemodynamical effects of administration of AS in FGR fetuses and to compare these effects with those that occur in appropriate for gestational age (AGA) fetuses. Secondary Objective(s): To investigate the effect of…
The main objectives of this study are: • To gain insight into the effectiveness of the Healthy Working Approach on need for recovery in elderly care workers over one year. • To gain insight into the process of implementing the Healthy Working…
The lifestyle program will improve the quality of life and lifestyle behavior, and will decrease the healthcare utlization, comorbidity and cancer recurrence rates.
Gastric fluid volumes in patients with a 6-4-0 pre-operative fasting regime are comparable to patients with a 6-4-2 pre-operative fasting regime
We hypothesise that standard anaesthetic management guided by mitoPO2 monitoring to optimise tissue oxygenation, using conventional measures, results in higher tPO2 during surgery and, therefore, a higher mean mitoPO2 over time.
The main clinical challenge remains to identify patients who may benefit from aggressive local treatment (stereotactic radiotherapy, SBRT) of soft tissue oligometastases: for which patients can systemic treatment be postponed? Patients who are…
Based on previous studies, we will expect that ambroxol improves neurological manifestations in patients with GD3.
We hypothesise that an anti-inflammatory dietary pattern (AIDP) has a beneficial effect on gut microbiome (diversity and permeability), thereby improving global functioning (measured with Outcome Questionnaire 45, OQ-45), and health of patients with…
We hypothesize that PARP inhibitors can potentiate radiation-induced tumor cell death in patients treated with PRRT. To determine the maximin tolerated dose (MTD) of this combination, a phase 1 dose-escalation study is needed.
The primary aim of this split-mouth randomized clinical trial is to assess accuracy of bracket positioning of a fully digital IDB workflow compared to a DBB workflow, with IDB bracket planning serving as reference for both methods. The secondary…
Short hydration during cisplatin chemo radiation is significantly more effective than long hydration in preventing acute kidney injury
The primary research questions are: 1. To what extent does a 4 week ReHab-TOAT regime lead to improvement of arm function in chronic stroke patients with either a severely or moderately affected arm-hand? 2. To what extent is any improvement of arm…
Blue light glasses can manipulate (i.e., inhibite) body melatonine production to re-adjust the circadian rhythm of shift workers, thereby having the potential to enhance viglance, cognitive function, and positive mood during night shift work.
We hypothesize that PHA-022121 will be more effective in both the treatment and prophylaxis of acute angioedema attacks in patients with acquired C1-inhibitor deficiency when compared to placebo.
Primary Objective: 1.To investigate whether daily electrical stimulation of gluteal and hamstring muscles combined with usual care is more effective in reducing recurrences of PUs than only usual care in individuals with chronic SCI, who often have…
The aim of this study is to evaluate the effects of platelet transfusions on hemostatic parameters in thrombocytopenic hematology patients and to identify other determinants of hemostasis, which may contribute to clot formation and clot strength.
We hypothesize that there will be a significant difference in anterior translation of the humeral head between patients and healthy objects. Secondly we hypothesize that the inter- and intra-rater reliability of the HHC test will be fair to good.…
Metabolic syndrome is a cluster of conditions that are associated with insulin resistance, hyperinsulinemia and type 2 diabetes (T2D). Pathophysiological conditions characterized by insulin resistance and hyperinsulinemia can lead to several, often…