2182 results
To determine the best dose escalation scheme of dipyridamole added to acetylsalicylic acid, based on the side-effect headache, in patients starting secondary preventive therapy for stroke
Primary objective: The primary objective of the study is to determine the effect of concentration/meditation on the innate immune response induced by a lipopolysaccharide (LPS) challenge. Secondary Objective(s): There are two secondary objectives:1…
The purpose of the present proposal is to improve care to children with asthma by including regular assessments of non-invasive inflammatory markers during the management of asthma. In this case, treatment is also guided by inflammatory markers (…
Hypotheses of the study:Psycho-education coping skills training is effective in reducing the negative consequences of stigma in people with SMI, in a way thata) quality of life of people with SMI improves;b) social functioning of people with SMI…
Evaluation of the rise in serum creatinine and the incidence of CIN following angiography in patients treated with a short hydration regime during 1 hour with sodium bicarbonate compared to a hydration regime with saline during 6-24 hours.
Primary: To characterize the QGE031 dose response relationship for the increase in the threshold dose of peanut protein that induces objective hypersensitivity reactions after treatment.Secondary (only key parameters): The percentage of patients…
Study question and objective At this stage of developement of the multicomponent is intervention it is unclear whether the intervention is feasible in practice. Therefore the question: Is this multicomponent preadmission intervention feasible in…
Primary Objective: To investigate the association between the weight-loss-induced cellular stress response and the rate of weight regain. Secondary Objective: To investigate the difference in cellular stress response and weight regain after rapid…
The objectives of this study are:- to evaluate the potential of dalcetrapib to reduce cardiovascular morbidity and mortality in adult patients with stable coronary heart disease (CHD), CHD risk equivalents or at elevated risk for cardiovascular…
The aim of the proposed pilot study is to explore the efficacy of rTMS in inducing a (transient) localized increase in brain activity of MS patients which is hypothesized to be beneficial for cognitive functioning. This is the first step that needs…
The primary aim of this study is to investigate the effect of imitation of a role model, the teacher, and the effect of convivial eating on the intake of a vegetable in children aged 4 to 6 years of age.The aim in a more long-term perspective is to…
To create and validate patient-specific post-OR M-S models of the lower limb of hip patients. The primary goal of this study is to see if the model can accurately predict how a patient walks after surgery given the pre-OR MRI scan and accurately…
The objective of the study is to investigate the effect of chewing gum with and without magnolia extract on the composition of dental plaque and saliva. In addition the influence of chewing gum on the wettability of the tooth surface will be studied…
The purpose of the proposed study is to investigate the anti-Xa levels of enoxaparin in patients after bariatric surgery and to correlate these with actual body weight.
The study will excist of two experiments. The first experiment is a two week overnight electrical stimulation program and in the second experiment subjects will be stimulated for 4 months.With these two experiments we wish to answer the following…
In this pilot study, we are setting on to investigate the differential effects of the VDR activator paricalcitol versus calcitriol on peritoneal transport, peritoneal inflammation and peritoneal defense parameters in PD patients.
to explore the effect of sodium intake on the coffee-induced increase in blood pressure
The primary objective of the present study is to evaluate the effect of a high soy protein diet on insulin resistance and glycemic control in participants with characteristics of the metabolic syndrome. Secondly, the present study will evaluate…
Aim of the study is to determine the microvascular function in type 1 diabetes patients with concomitant celiac disease
The effect of NEAT or inactivity on insulin sensitivity and lipid metabolism is unclear. The objective of the present study is to evaluate the effect of 4 days of mainly sitting, or sitting and walking, or sitting, walking and biking on glucose and…