5 results
This study is therefore aimed at quantifying the relative contribution of the two major receptor systems involved in S(+)-ketamine and methadone induced analgesia and side effects (respiratory depression, sedation, miosis).
The primary objective of this study is to compare the acute effects of single doses of methadone (5 and 10 mg) and buprenorphine (0.2 and 0.4 mg) with placebo on driving performance and cognition. Secondary objective is to study the pharmacokinetics…
Primary:• To evaluate the safety of ORGN001 (formerly ALXN1101) over the first 6 months of treatmentSecondary:• To characterize the pharmacokinetics (PK) of increasing doses of ORGN001 (formerly ALXN1101) • To evaluate the effect of ORGN001 (…
Primary objective 1) To evaluate the usability of the total viQtor solution applied and used 24/7 in clinical practice.This includes the ease of use and/or usability of:the wearable, charger and armband by the primary participants/usersthe *care…
The primary objective of this study is to compare effectivity of suboxone and methadone on reducing opioid misuse.Secondary objectives include comparing the effects of these two medications on pain, well-being and medication use.