8 results
To determine the toxicity of adding chloroquine in escalating doses in patients with small cell lung cancer to standard therapy.
To determine the toxicity of adding chloroquine in escalating doses in patients with small cell lung cancer to standard therapy.
Primary objective (parasitological): To induce protection against malaria by exposure to infectious mosquito bites under chloroquine prophylaxis. Secondary objectives (immunological): 1. To induce an effective immune response against natural malaria…
Primary objective * To determine the maximum tolerated dose and recommended dose of metformin plus chloroquine in patients with IDH1/2MT glioma, IHCC and CS Secondary objectives * To describe the toxic effects of metformin plus chloroquine in…
Study whether chloroquine as comedication results in a better respons on Hepatitis B vaccination in non-responder dialysis patients.
Primary objective:Does addition of azithromycin to standard chloroquine treatment result in a higher clinical cure rate at day 7 than treatment with chloroquine alone in patients with COVID-19.Cure is considered when 4 criteria are present:(1) O2…
Primary objective• To determine the MTD/RPTD for CQ in combination with concurrent radiotherapy with daily TMZ in patients with a newly diagnosed GBM.Secondary objectives• To characterize the safety and tolerability of CQ in combination with…
The objective of this study is to confirm procedural performance of the Exalt single-use duodenoscope in Endoscopic Retrograde Cholangiopancreatography (ERCP) or other duodenoscope-based procedures.