4 results
Primary objective The primary objective of the study is the evaluation of the therapeutic benefit of three repeated dose intratympanic AM 101 injections in comparison to placebo in the treatment of persistent acute inner ear tinnitus following acute…
Primary:* Phase I: to establish the recommended phase II dose (RP2D) of BCT-100 in children andyoung adults as assessed by dose limiting toxicity (DLT) and complete arginine depletion.* Phase II: to determine the activity of single agent BCT-100…
Phase 1:The primary objective of this trial is to investigate whether oral esketamine is non-inferior to ECT after eight weeks of individually optimized treatment, in participants with NTRD.Phase 2:To compare the efficacy of maintenance oral…
To investigate whether oral esketamine is non-inferior to ECT in achieving treatment response on depression severity in NTRD.