3 results
Approved WMOCompleted
The primary objective of this study is to evaluate the target engagement of AZD4831, MPO inhibitor by measuring MPO specific activity in plasma following ex vivo stimulation of fresh blood samples with zymosan, in patients with HFpEF. MPO is known…
Approved WMOCompleted
To test the safety and feasibility of a closed loop controller of the FiO2 based on the measured SpO2 in a NICU setting.
Approved WMORecruiting
This study aims to evaluate the effect of AZD4831 on functional improvement and reduction of symptoms in participants with heart failure with left ventricular ejection fraction > 40%. Additionally, the PK and overall safety profile of AZD4831…