3 results
Approved WMORecruiting
(1) to establish the effect of adding amiloride to lithium- treatment on the progression of renal insufficiency in patients with lithium- nephropathy (2) to answer the question whether adding amiloride to the use of lithium has the same effect as…
Approved WMOPending
To compare the effect of amiloride on lithium-induced Nephrogenic Diabetes Insipidus with the effect of hydrochlorothiazide, measured as urine volume and maximal urine osmolality.
Approved WMOWill not start
Primary objective: to investigate the effect of amiloride on urine volume and urinary concentrating ability in patients on chronic lithium therapy suffering from polyuria.We hypothesize that amiloride therapy will improve urinary concentating…