2 results
Approved WMORecruiting
The objective of this study is to validate a novel MRS-based method to quantify NAD+ by selectively suppressing the coupled *-ATP spin system, which is overlapping with the NAD+/NADH signals in vivo. For NAD+/NADH quantification to be valuable in…
Approved WMOCompleted
Parts D and E: Primary Objectives:• To evaluate the safety and tolerability of VX-445 in TC with TEZ and IVA in subjects with cystic fibrosis (CF)• To evaluate the efficacy of VX-445 in TC with TEZ and IVA in subjects with CFSecondary Objectives• To…