3 results
Approved WMOCompleted
Primary outcome:The effect of Pyridostigmine (cholinesterase inhibitor) on inflammatory signs as pain, temperature and swelling of the extremity measured according to TREND protocol (appendix 1).Pain is measured according to VAS scale, temperature,…
Approved WMOCompleted
to investigate the effect and efficacy of pyridostigmine on muscle strength and fatiquabillity in patients with SMA.
Approved WMOCompleted
Primary:- To evaluate the safety and tolerability of repeat doses of GSK2831781 during the Induction Phase.- To characterise the efficacy dose-response of GSK2831781 during the Induction Phase.Secondary:- To evaluate the safety and tolerability of…