4 results
Use of iron chelation therapy has demonstrated benefits in terms of morbidity and mortality for chronically-transfused thalassemia patients with iron overload. Recent retrospective data (Leitch 2007, Rose 2010, Sanz 2008) suggest that overall…
The primary objective of the study is to determine concentration of circulation cytokines na administration of LPS in the presence of iron sucrose (Venofer®), Deferasirox (Exjade®) of placebo.
This pilot study aims to confirm the feasibility of the PET scan procedure in 4 healthy volunteers to quantify NET binding in humans. This would then lay the foundation for intended future studies in our department investigating NET availability in…
To study the safety and efficacy of deferasirox as treatment of oxidative stress in adult subjects with sickle cell disease.