131 results
"The primary objective of this study is to evaluate the fixation and migration patterns of the Persona Partial Knee (Zimmer Biomet, Warsaw, IN) in vivo, using model-based radiostereophotogrammetric (mRSA) analysis. The secondary objective is to…
We expect that the development of mitochondrial dysfunction lags behind the development of the hypermetabolic inflammatory state. Additionally, we hypothesize that the aggravation of factors related to the hypermetabolic inflammatory status, such as…
The primary aim of this split-mouth randomized clinical trial is to assess accuracy of bracket positioning of a fully digital IDB workflow compared to a DBB workflow, with IDB bracket planning serving as reference for both methods. The secondary…
To assess the PK/PD relationship of prednisolone as either prophylaxis or therapy of GVHD in children after HCT.
The primary objective of the present study is to examine the therapeutic effect of the Carbon Hand system on handgrip strength in patients with hand function problems, after using the glove for six weeks at home. Secondary objectives are related to…
Investigate the effect of having CYP2C19 and CYP2D6 genotypes at start of antidepressant therapy and it’s cost-effectiveness in the primary care setting.
The use of an interactive web-based Decision Aid reduces decisional conflict and increases patient satisfaction with information and care.
Our primary objectives are to determine the diagnostic accuracy of handheld RCM in the diagnosing and subtyping of BCC in the head and neck compared to punch biopsy, and evaluate the associated rate of over- and understaging of BCC subtypes. In…
We hypothesize that the fertility enhancing effect of OSCM during HSGs is also present during THL.
The use of an interactive app during the perioperative period, when undergoing colorectal surgery, will activate and stimulate patients and therefore result in higher compliance to the ERAS-protocol.
The standard-of-care sentinel lymph node (SLN) procedure in paediatric cancer patients consists of a preoperative intradermal injection with 99mTechnetium-nanocolloid as radiotracer in combination with an intraoperative injection of blue dye for…
We hypothesize that the T2T strategy is superior compared to the T2S in retaining gout remission and is also more cost-effective.
Point of care testing with Fcal POCT will reduce substantial the referral rate of children with chronic GI symptoms to the paediatrician.
The primary objective of this study is to determine patient perspective of and satisfaction with follow-up type and frequency after THA and TKA. Therefore, we will send surveys to patients who had a THA or TKA between 1 and 15 years ago.
There might be discrepancies in number and type of Cancer Predisposition Syndrome diagnoses between the genotype first and the phenotype first approach.
The different processing of formulas will have an effect on stool characteristics such as consistency, frequency, amount and colour.
The experimental treatment (game-supported TPM training) will contribute to a more effective generalisation of compensatory strategies to untrained tasks as compared to the active control group (CogniPlus training).
We hypothesise that patients in the intervention group will show a reduction in sedentary time of at least 60 minutes per day after the cardiac rehabilitation program, compared to a reduction of maximally 30 minutes per day in the control group.
Effective postoperative pain control is an essential and humanitarian need of every surgical procedure. Inadequate pain control may result in increased mortality, delayed recovery and increased hospital costs (1). The optimal perioperative analgesic…
The primary objective of this study is to evaluate the effect of surgical correction of pes equinovarus deformity compared to conservative treatment on personalized goal attainment. In addition, we will evaluate the effect of surgical correction of…