706 results
To evaluate the long-term effects of early intervention in high-risk infants on the basis of the VIP-project.
Primary objectives:1a. To determine the severity and course of obstructive sleep apnea in children with congenital mandibular hypoplasia (both isolated and syndromal).1b. To determine the growth pattern of the lower face in relation to the upper…
Aim of the present study is to investigate whether LIFT or TAFR is the preferable treatment for high transsphincteric fistulas-in-ano of cryptoglandular origin.
The objective of this study is to determine the effectiveness of the CHA2DS2-VASc prediction model as directive for the preventive management of AF patients in the first line.
To compare in a randomized controlled trail (RCT) the risk of neonatal hyperbilirubinaemia between neonates treated with CFT and amoxicillin-clavulanic acid (augmentin, AUGM) combination versus neonates treated with the aminoglycoside, tobramycin (…
The primary objective is to assess whether renal denervation added to usual care compared to usual care alone reduces BP (office based BP and 24-h ambulatory BP-monitoring) both in subjects with a SBP level above 160 mmHg as well as subjects with a…
Our aim is to determine the effect of APO* on activity and volume of the hippocampus, a core structure of Alzheimer pathology, at a young age. Specifically, we aim 1) to determine the effects of APOE e4 on hippocampal activation in the young general…
The main objective of this pilot study is to determine the effects of vascular access construction on autonomic and cardiac function.
Objective: To determine the (added) value of molecular imaging techniques for selecting patients that will benefit from CRT.
To establish the efficacy of 60 mg baclofen compared to placebo in inducing a decrease in food craving, as assessed by a food craving questionnaires (G-FCQ-T) over 6 months in obese subjects.
We aim to investigate thirst in the above mentioned patient groups, applying a Visual Analogue Scale (VAS) and, where ethically acceptable, a new thirst provocation test which we will develop in a group of healthy probands. Using these tools, we aim…
to develop a *two hit* in vivo autologous RBCs transfusion model in healthy male volunteers.
Firstly, to study the reduction in sick-leave time achieved by the treatment protocol. Secondly to study the quality of life in the patients treated in the fast-track protocol, to study the reduction in societal costs and to stdy the efficacy of a…
1. the primary objective of this study is to examen the incidence and prevalence of PTSDand depression in pre-eclampsia patients after delivery2. a secondary objective is to identify risk factors during pregnancy, durante partu and postpartum…
In this pilot study, the objective is to show an improvement in glucose tolerance,a decrease in parameters for inflammation, oxidative stress and a procoagulant state after 4 weeks of daily supplementation of L -glutamine and Epigallocatechin-3-…
- To assess the safety and tolerability of escalating single and multiple IV doses of SAR228810 in AD patients- To evaluate the pharmacokinetic properties of SAR228810 in plasma and CSF after escalating single and multiple IV doses of SAR228810 in…
Primary: To compare the efficacy of aripiprazole with placebo in the suppression of tics in children and adolescents (7-17 years) with a diagnosis of Tourette*s Disorder. The primary efficacy measure is change from Baseline to endpoint (Week 8) on…
The objective of this study is to investigate the relation between tamoxifen use during COS, endoxifen levels reached during COS, and recurrence-free survival (locoregional recurrence, distant recurrence or death from any cause) when compared with…
The first objective of this pilot is to determine the feasibility of the measurements of the blood circulation in patients during the last phase of life. The second objective is to survey the quality of the blood circulation, particularly the…
To compare the EPOS guideline with the free choice treatment of the GP for acute rhinosinusitis in general practice.