105 results
To create and validate patient-specific post-OR M-S models of the lower limb of hip patients. The primary goal of this study is to see if the model can accurately predict how a patient walks after surgery given the pre-OR MRI scan and accurately…
To evaluate neurologic- and cognitive disorders, neuroimaging and ophthalmological alterations in perinatally HIV-infected children in comparison to matched (with respect to age, sex, race, home environment and socio-economic status) healthy…
Primary: To determine trends in nasopharyngeal colonization with total vaccine- and non-vaccine serotypes of S. pneumoniae in healthy 11-month-old and 24-month-old infants who have been immunized according to the Dutch National Immunization Program…
The main objective is to determine whether medication-free adolescents with ADHD show impairments in affective and complex social cognition. The secondary objectives are: 1) To determine whether the use of stimulant medication (on and off) affects…
To confirm superiority on glycaemic control of liraglutide versus placebo after 26 weeks of treatment when added to pre-existing basal insulin analogue treatment (with or without concomitant metformin treatment) in subjects with type 2 diabetes.
The primary objectives of the study are to:• Evaluate efficacy of 24 weeks treatment with RO4917838 in the PANSS negative symptom factor score in patients with persistent, predominant negative symptoms of schizophrenia treated with antipsychotics.•…
The primary objective is to evaluate clinical hindfoot outcome (e.g. pain, function, alignment) in patients that underwent subtalar joint arthrodesis due to painful post-traumatic subtalar joint osteoarthritis following operative treatment of an…
Objectives: Part 1) To assess the prevalence of PA in general practice (part 1 of this study);Part 2) To describe differences of cardiorenovascular damage in newly diagnosed hypertensive patients with versus without PA (part 2 of this study);Part 3…
- To elucidate whether simultaneous measurement of brachial BP may improve the accuracy of assessment of interarm BP differences compared with sequential interarm BP assessment
To detect high-risk pathogenic mutations in germline DNA of children with childhood cancer that are suggestive of genetic predisposition, using NGS-based whole-exome sequencing, resulting in novel targets for future functional and translational…
The objective of the study has the intention to prove that a pre-and dysmature baby in a supported back-position, by the use of a controlled moulder, shows more signs of comfort than a specific baby in a freely supine position.We are basing…
- to examine the safety and tolerability of the research medication- to examine how the research medication is absorbed, broken down and excreted by the body.
The primary objective is to examine the effectiveness of (the different components of) Featback with regard to the primary and secondary outcome measures. The secondary objective is to examine predictors, moderators and mediators of intervention…
The main objective of this proposal is to request permission for recruitment and participation of individuals between ages 8 and 30 in an fMRI session and several behavioral testing sessions. These studies are aimed at relating brain development to…
Primary objective:- To evaluate the safety and tolerability of single ascending doses of ASP3652 in healthy young Caucasian male and female subjectsSecondary objectives:- Different pharmacokinetic outcomes- Different pharmacodynamic outcomes
The objective was to assess the effectiveness of low-dose aspirin in the prevention of recurrent preterm birth.
Smell and taste function change during chemotherapy consequently affecting 1) dietary intake 2) eating behavior 3) anthropometry 4) quality of life
We expect that the use of the flexible IM rod results in a post-operative sagittal contour of the distal femur that resembles the pre-operative situation, i.e. a better fit of the prosthesis, when compared to the use of the the standard IM rod
To analyze the number of patients with (germline/somatic) actionable molecular aberrations in patients with relapsed/refractory pediatric tumors for whom no standard treatment or study protocol is available.
The primary objective of this study is to determine patient perspective of and satisfaction with follow-up type and frequency after THA and TKA. Therefore, we will send surveys to patients who had a THA or TKA between 1 and 15 years ago.