12 results
1. To improve the overall outcome as compared to the previous protocols of the DCOG, especially ALL-9 and ALL-10. This is aimed for by decreasing therapy for part of the patients (TEL/AML1, Down syndrome, PPR only), increasing therapy for IKZF1…
The use of an interactive web-based Decision Aid reduces decisional conflict and increases patient satisfaction with information and care.
Primary objectives: - Overall: Improvement of event-free survival (EFS) probabilities in childhood relapsed ALL - Randomization 1: EFS of Arm A (ALL-REZ BFM 2002) versus B (ALLR3) in SR patients - Randomization 2: Influence of epratuzumab…
The standard-of-care sentinel lymph node (SLN) procedure in paediatric cancer patients consists of a preoperative intradermal injection with 99mTechnetium-nanocolloid as radiotracer in combination with an intraoperative injection of blue dye for…
Hypothesis: Percutaneous nephrostomy is non inferior to retrograde double J catheter regarding time to clinical recovery. Secondly, patient reported outcome measures (PROMS) comparing treatment room and OR settings of drainage procedures will most…
To evaluate the effectiveness of eccentric calf muscle exercise therapy compared to strength training of the upper extremities (control group) in patients with chronic midportion Achilles tendinopathy.
Primary Objective To describe how patients experience the first eight weeks after shoulder arthroplasty, regarding pain and pain medication, shoulder function and quality of life. To determine the direct effect of patients' expectations on…
Primary Objective: - Achieving an event-free survival, which is not inferior to the ML-DS 2006 trial (87±3%) Secondary Objective(s): - Reduction of toxicity: severe adverse events (CTCAE v4.0 grade III or higher) - Evaluation of…
Primary objectives: Improvement of CR2 rates after induction with ALL R3 with bortezomib versus without bortezomib in HR relapsed ALL patients Secondary objectives: Improvement of Event Free Survival (EFS) and overall survival (OS) rates…
Patients in the intervention group will be stimulated to increase their level of PA and protein intake after hospital discharge by using multiple behavioural change techniques. Higher levels of PA and achieving protein requirements are expected to…
This study will investigate the potential value of CFX treatment, by prospective monitoring of functioning in patients that undergo this treatment. Likewise, aspects of the treatment that are important for patient experience will be systematically…
The study objective of the trial was to test the hypothesis that treatment with mepolizumab only affects inflammatory eosinophils whereas treatment with benralizumab affects both inflammatory and resident eosinophils.