12 results
Tumor-positive lymph nodes in patients with early EAC can be accurately detected through a sentinel node procedure.
There might be discrepancies in number and type of Cancer Predisposition Syndrome diagnoses between the genotype first and the phenotype first approach.
REE will be assessed using indirect calorimetry. Oxygen consumption (VO₂) and carbon dioxide production (VCO₂) will be measured. The respiratory quotient (RQ) will be derived from VO₂ and VCO₂. Body composition will be determined by…
Both interventions (GRAIL training & endurance and strength training (control intervention)) will result in an increase in gait speed, functional walking ability and social participation. However, the GRAIL training will result in larger…
Primary objective: To classify the effect of the pharmacogenetic profile of CYP2C19 and CYP2D6 in HD gene expansion carriers on negative medication effects of HD-related medication with an actionable drug-gene interaction in the…
We hypothesize that the risk of any congenital abnormality in fetuses with an early increased NT that normalizes, will be lower than those with persistent increased NT after 11 weeks of gestation.
Active surveillance is non-inferior to surgery in patients with oesophageal cancer showing complete clinical response after neoadjuvant chemoradiotherapy.
The new treatment algorithm for patients with high-risk T1b EAC consisting of radical ER of the tumor, followed by a sentinel node procedure with selective lymphadenectomy is feasible and safe.
Primary objectives: 1. Assess the feasibility of FMT in PD patients. 2. Assess the safety of FMT in PD patients. Secondary objectives: 1. Explore whether FMT leads to alterations in motor complications (fluctuations or dyskinesias) and…
To establish the diagnostisch accuracy of ultrasound for the exclusion of fracture of the elbow
The main objective of the study is to assess the change in first morning void urine albumin-to-creatinine ratio across the study period. The secondary objective is to assess changes from baseline in systolic blood pressure, body weight, eGFR and…