248 results
Based on the human milk composition, Nutricia Research has developed a new infant formula with a new fat blend, more similar to that of human milk. This new formula is currently being studied for safety and its effects on growth. The comparator used…
HCQ causes both autophagy inhibition and chromatin modification, thereby (re)sensitizing tumor cells to EGFR TKIs, hypothetically increasing response rates after one week.
The effectiveness of an indicated indicated depression and anxiety prevention program ('Een Sprong Vooruit') will be tested in a Dutch sample of adolescents (aged 11-15) with high familial risk. It is expected that the adolescents who…
Antipsychotics (haloperidol) can cause acute changes in cardiovascular functions, metobolic parameters and platelet aggregation in elderly patients.
We hypothesise that fasting-induced insulin resistance will result in decreased glucose uptake and activity of brown adipose tissue (BAT). In addition, prolonged fasting will lead to reduced mitochondrial uncoupling in skeletal muscle, which is…
There will be a relation between the level lidocaine in newborn, the level in mother and drug-delivery interval.
We hypothesize that motivational and behavioral characteristics of eating behavior, in addition to genetic and environmental factors play a major role in the development of obesity. We aim to identify obesity subtypes based on these factors.
In this research we will investigate if i.v. iron therapy can become a method of blood saving therapy for orthopedic surgery and can replace erytropoietin.
Congenital cytomegalovirus infection can cause long term sequelae including hearing loss and cognitive impairment.
We assess the prevalence and seriousness of DDIs among ambulatory cancer patients on anti-cancer treatment.
The robotic-assisted technique will allow the ascertainment of ‘Critical View of Safety’ in all anatomical variations.
Uterine cervical cancer is the second most common female malignancy. Therapy monitoring is essential to detect early recurrence. Diffusion-weighted magnetic resonance imaging is an emerging MRI imaging technique which has a potential value for the…
A vaccumcurettage in persistent trophoblactic disease decreases the number of chemotherapy cycles needed to obtain normalisation of the hCG level.
We hypothesise that Origo, an experience design concept that supports the woman during labor in a personal and unobtrusive way by providing real-time breathing support and visualizing progress of labor, will enhance the woman s labor &…
The aim of this study is to assess the ability of PET using [18F] fluorothymidine (FLT), an imaging biomarker, performed at week 10 of treatment can discriminate between pseudo progression and true progression as measured by MRI at 10 and 22 weeks,…
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To determine the current views of medical residents and educators on current assessment methods of care management competencies and potential assessment tools that can be used to improve care management evaluation. PHASE 3: 1. Literature review to…
The purpose of this study is to evaluate the feasibility (safety and effectiveness) of the AEGEA GEA System to reduce menstrual blood loss in women with a history of menorrhagia due to benign causes.
The hyperfiltration hypothesis implies that children with a solitary functioning kidney are at risk to develop hypertension, (micro)albuminuria and chronic kidney disease. We aim to develop an individualized risk profile for children with a solitary…