544 results
There might be discrepancies in number and type of Cancer Predisposition Syndrome diagnoses between the genotype first and the phenotype first approach.
REE will be assessed using indirect calorimetry. Oxygen consumption (VO₂) and carbon dioxide production (VCO₂) will be measured. The respiratory quotient (RQ) will be derived from VO₂ and VCO₂. Body composition will be determined by…
Adequate perfusion of an adult-sized renal graft in children demands significant hemodynamic changes after transplantation (Tx). Suboptimal renal graft perfusion due to inadequate hemodynamic adaptation increases the risk of loss of renal graft mass…
The primary objective is to examine whether changes over time in monitoring measures of cognition and behavior are associated with functional outcomes in pediatric oncology groups. Additional objectives are to examine trajectories, risk factors, and…
The aim of our descriptive study was to quantify the disease burden leading to hospital-based care, repatriation or death in Dutch travelers during their stay in a foreign country, including Europe. The outcome of this study could be used as…
To assess normal values of echocardiographic parameters and exercise tolerance as asssessed by bicycle ergometry in healty schoolchildren 12-18 years old.
The aim of this project is to collect new normative data for the Dutch children, for both parts of the M-ABC2. The opportunity will also be taken to extend the age range of the test down to 3 years and up to 16 years. Also the reliability and the…
Effectiveness of treatment with clioquinol on parasitologic eradication is being studied as well as the clinical effectiveness of eradication in children with dientamoeba fragilis infection.
The aim of the study is to improve the quality of life of cystinosis patients. Part of it forms neuropsychological screening in order to identify specific defects in the neurocognitive development and learning abilities. The results will contribute…
To see if there is a clinically relevant and statisticallly significant decrease in lung function when children with mild to moderate persistent asthma feel the need to take bronchodilators.
1) To examine whether adolescents with depression, show abnormalities during specific attentional processes, compared to normal controls, 2) To determine whether abnormalities in attentional processes can be considered as prognostic markers of a…
To identify novel childhood cancer-predisposing genes in children.
The present study aims at exploring a visuo-tactile mirroring mechanism in patients with autism. Furthermore, the relationship between neural tactile simulation processes, empathic abilities, and symptom severity in the social domain will be…
The aim of this study is to describe the values of the SNIP in patients with neuromuscular disease and various respiratory conditions and to assess the practicability of the SNIP in these patients.
a. analysis of the usefulness of new molecular biological techniques in the diagnostic process of short stature, especially the detection of small chromosomal anomalies.b. identification of genetic factors causing short stature or influencing the…
The aim of the study is to archive an objective measure for auditory processing disorders, using the P300 measurement, an auditory event related potential. This to be able to discriminate between children with and without auditory processing…
- To determine physical fitness in children with a congenital heart disease (ventricular septum defect, atrium septum defect, tetralogy of Fallot, transposition of large arteries and patients after a (modified) Fontan-operation) and to compare…
The goal of this study is to improve risk stratification and treatment allocation for medium and high risk neuroblastoma patients by real time quantitative (RQ)- PCR-minimal residual disease (MRD) testing.We have recently developed a panel of RQ-PCR…
The objective of the study is to assess the long-term safety of tacrolimus ointment 0.03% or 0.1% in the treatment of subjects with atopic dermatitis under actual use conditions, including the risk of developing cutaneous or systemic malignancies.…