14318 results
Primary Objective: The treatment result expressed as the proportion of successful treatments per treatment arm (successful = VUR <= grade 1 and/or no urinary-tract infections 6 months after the operation) does at least not show a significant…
To assess whether changes in insulin sensitivity through dietary interventions affect postprandial bile acid metabolism and kinetics. Secondary objective: to assess TGR5 and FXR mediated pathways in insulin resistant and insulin sensitive states.
In our previous studies using optical spectroscopy, both ex vivo and in vivo, most promising results were obtained for tissue diagnosis. Moreover, invasive procedures for biopsy or radiofrequency ablation in these tissues are all very common. Thus,…
The goal of this study (mono-center study) is to study the effect of renal denervation with the EnligHTN Renal Denervation System on sympathetic nerve activity.
In this study we want to objectively measure the effect of Pirfenidone on cough in patients with IPF.
Distinguishing frontal lobe epilepsy from ADHD in terms of working memory.
The primary objective of this Registry is:• To evaluate HCV viral sequences and the persistence or evolution of treatment emergent viral mutations in subjects who fail to achieve an SVR after treatment with a Gilead oral antiviral containing regimen…
Our study will measure several different symptoms/aspects of cellulitis, such as redness, swelling, warmth, pain, fluctuation, ulceration and drainage. Each of these aspects will be scored on a scale of 0-3, adding up to a maximum total score of 21…
The major goal of this study is to develop a systematic and stepwise approach for dry eyes. First, it will be evaluated whether Tes glasses are a diagnostic tool for dry eye diseases. Second, it will be evaluated or it can make a distinction between…
With this study we will investigate the effects of lumbar sympathetic blockade on ERPF and measured GFR and relative changes in non - invasive hemodynamics measured before and after continuous lumbar sympathetic blockade or splanchnic blockade in…
Identify DNA methylation markers suitable for sensitive and specific plasma-based detection of advanced colorectal adenomas.
Primary Objectives-To evaluate if mitochondrial dysfunction can be induced in healthy, middle aged subjects, through the use of simvastatin, and whether it can be reversed by oral ubiquinol supplementation. -To validate the techniques NIRS, PpIX-…
The main objectives of this study are to (I) investigate characteristics of children and adolescents with CD and/or ODD in comparison with typically developing (TD) controls and (II) examine subtypes of aggression on the behavioural, cognitive,…
To characterize the safety and tolerability of long-term administration of evolocumab in subjects with known coronary artery disease andhypercholesterolemia.
1. To identify and quantify the structural airway wall layers with OCT and rEBUS and correlate this to histology and HRCT2. To identify and quantify the effect of bronchial thermoplasty on the airway wall layers by OCT and rEBUS and correlate this…
The primary objective is to evaluate the difference in 68Ga-exendin tracer accumulation in the pancreas of patients with and without complete resolution of T2DM after RYGB by quantitative analysis of PET images.
The objective of the study is to investigate if it is possible to predict the clinical outcome of a patient with SCN1A related epilepsy based on the findings of advanced genotyping. We aim to answer the following questions:1. Can clinical outcome in…
A pilot study of the feasibility of 11C-MET as postoperative baseline scan in the follow-up of high-grade gliomas for the detection of tumor recurrence.
Primary Objective: The objectives of this study are to assess lumen, scaffold, vessel dimension, malapposition and tissue coverage as assessed by quantitative angiography, intravascular optical coherence tomography and intravascular ultrasound…
Objective: The aim of this study is to assess the validity of the 4MGS and 5STS to determine the functional exercise performance of PF patients.