312 results
Current approaches to study and diagnose SVD focus on lesion-detection with MRI. However, SVD-lesions represent an end-stage and are insufficiently specific to understand disease processes. It would be a major advance if SVDs in humans could also be…
We expect that depressive adolescents will show a stronger increase in heart rate during, as well as a slower recovery afterwards, when they are left in the game or when they encounter fearful stimuli compared to non-depressive adolescents. Finally…
Morbidity in the post-operative phase of pulmonary surgery is characterised by impairment due to pain, dyspnoea and loss of exercise tolerance. We demonstrated previously that rehabilitation after thoracotomy is limited due to pain. Since minimal…
Maternal and neonatal vitamin D level play a role on dental development in childhood
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
The COL3A1 polymorphism is a inheritable genetic defect, responsible for the increased susceptibility to pelvic organ prolapse in women.
Fatigue affects central nervous system function and, in the setting of the medical profession, could influence specialist performance, patient care and safety. ln contrast to other industries, for example the aviation industry, there are no "…
Non invasive hemodynamic monitoring is as good as invasive monitoring
Combining FOLFIRINOX chemotherapy and stereotactic radiotherapy can lead to better regional tumor control and better overall survival in patients with locally advanced pancreatic cancer.
Primary objective: To determine the safety of once daily inhalation of the recommended daily dose of tobramycin with the Akita® and the PARI-LC® Plus nebulizer in patients with CF. Systemic absorption can be used as surrogate parameter for safety.…
The acquired brain dysfunction after critical illness in the neonatal period has led to problems with the translation of visual information (e.g. determining the position and speed of the ball) into a goal-directed motor action (i.e. a coordinated…
* Mortality among adult ischaemic and intra-cerebral haemorrhagic stroke patients admitted to an Intensive care Unit (ICU) is higher compared to other critically ill populations, subdivided into predefined diagnostic groups, over time and regardless…
The aim of the study is to explore the relation between frailty, functional status and other patient characteristics and adverse outcomes as functional decline, length of stay, admissions and mortality. Frailty is multifactorial and is known to be…
We hypothesize that the deformation-volume loop will help to identify the consequences of aortic stenosis and the changes in functionality after aortic valve replacement (AVR)
1) Pre-sleep whey protein ingestion stimulates overnight muscle protein synthesis rates 2) Pre-sleep casein protein ingestion stimulates overnight muscle protein synthesis rates 3) Pre-sleep whey and casein protein do not differ in their impact on…
The prevalence of disinhibited behavior is high in institutionalized people with the behavioral variant of frontotemporal dementia. Disinhibited behavior is associated with reduced well-being of residents and is experienced as an important challenge…
It is hypothesized that the multi-species probiotic formulation Winclove CLEAR may reduce the incidence- and symptom severity of urinary tract infections in women and thus improve patient quality of life