788 results
Primary Objective: The treatment result expressed as the proportion of successful treatments per treatment arm (successful = VUR <= grade 1 and/or no urinary-tract infections 6 months after the operation) does at least not show a significant…
To improve the response rate to treatment of severe acute GVHD (grade II-IV with gut involvement ) by adding infusion of Mesenchymal Stroma Cells to standard high dose prednisolone.
The main objectives of this study are to (I) investigate characteristics of children and adolescents with CD and/or ODD in comparison with typically developing (TD) controls and (II) examine subtypes of aggression on the behavioural, cognitive,…
The primary objective is investigating the effectiveness of *Mindlight* in treating (sub)clinical symptoms of anxiety in children who are diagnosed with an autism spectrum disorder. The secondary objective is to examine the factors that moderate and…
This is a phase I/II pediatric dose-ranging study that will evaluate the safety, tolerability and pharmacokinetics of midostaurin in children <18 years of age and >= 3 months who have relapsed or refractory leukemias that may benefit…
Development and validation of the D-AI KIDS and the D-AI YA:Currently there is no standardized instrument that measures visually impaired children*s and young adults' participation based on the nine ICF-CY domains. The primary objective of this…
The objective of this registry is to obtain long-term safety and clinical statusinformation on pediatric patients with IBD (ie, CD, UC, or IC).
This study had two objectives:1. which factors determine outcome of treatment of children with functional childhood constipation referred to the outpatient clinic of multidisciplinary treatment clinics in the Netherlands;2. which factors can be…
Primary objective: to evaluate the image quality between the two protocols using Signal to Noise Ratio (SNR) measurements Secondary objectives: 1) test if measurements of lung volume and central airways dimensions using MRI are related to validated…
To study whether CMR analysisdifferences in aortic stiffness and myocardial lipid accumulation between SCT recipients and healthy, age-matched controls
The first objective of this study is to evaluate by direct laryngo-tracheoscopy the possible role of cuffed versus uncuffed tracheal tubes in producing airway injury in infants and children who were previously more than 24 hours intubated. The…
To evaluate the effects of intranasal oxytocin compared to placebo administration on appetite, satiety and food intake.Also effects on social behavior, BMI, body composition, IGF-I levels and genetic differences (deletion / mUPD). To assess oxytocin…
The major objective of this pilot study is to delineate SAD endophenotypes by investigating information processing characteristics, brain activity and connectivity, within the two key dimensions relevant to the SAD symptomatology: attention and…
The aim of the present study is to investigate the reproducibility of upper extremity strength measurements in children with CP. The following strength measurement instruments will be studied: Hand Held Dynamometry (HHD), pinch- and grip strength…
1. The application of 4D flow MR imaging to analyse blood flow patterns (flow angle, flow asymmetry), regional vessel wall parameters (regional wall shear stress, vessel wall thickness) and pulsed-wave velocity in neoaortic root, carotid artery and…
The main aims of our study are 1) to make a clinical inventory of MD cases, 2) to identify (modifier) disease genes underlying MD and 3) to link the clinical data with the genetic data in a data-base.
The objective of this study is to investigate the use of retinal oximetry in children, between five and seventeen years of age, with (vitreo-) retinopathies and oxygen-related diseases of the retina by means of an Oxymap T1 fundus camera.
This study aims to gain more insight in the sexual development of adolescent boys with ASDs.The main research question is: How do high functioning boys with ASD develop sexually? The main research question is worked out in 2 parts/1. Which sexual…
Primary objective:To compare the change in small airways obstruction (FEF75%) in patients with CF when inhaling one ampule of inhaled tobramycin with the Akita® compared to standard of treatment (twice daily nebulization of one ampule using standard…
The objective of this study is to evaluate whether an in- or outpatient initiation of the brace treatment has an influences short and long term brace compliance.