2654 results
To study the effects of transient severe endogenous stress hormone exposure on the structure and functioning of brains circuitry regulating emotion, and the association with cognition and psychopathological symptoms.
Primary Objective:The overall aim of the study is to examine whether the early-childhood adversities experienced by the adoptees will be transmitted to the next generation or whether the cycle of early negative experiences has been broken.Secondary…
The research focuses on the active screening of high prevalence patients and the diagnosis of AAA. This study aims to establish an effective screening protocol and determining a higher prevalence in patients with PAD and patients with carotid…
Our overall objective is to better understand the role of regulatory B cells in disease pathogenesis and to better predict disease flares in order to individualize treatment.
In the proposed project we aim to predict falls in daily life and to identify both aging- and disease-related impairments that underlie impaired postural control and an increased risk of falling in daily life.
At the stroke unit, exposure to the *Dynamic Adaptive Healing Light System* (DAHLS) following a predefined daily rhythm with low, medium or high intensities dependent of the medical status of the ischemic stroke patient is expected to improve the…
Clinical, prospective, non-randomized trialOrbis Medsich Centre, Sittard-Geleen
The aim of this study is to assess the change of ammonia exhaled in Helicobacter pylori (HP) positive patients compared with patients that are not HP infected after urea administration. In principle, in this pilot study, the results of Kearney et al…
We propose to perform a pilot study to examine the feasibility of studying the triangular association between: 1) amino acid metabolism (influenced by, amongst other factors, diet composition [e.g. energy intake, macronutrient intake, individual…
Primary objectives: 1) Study EF in general and WM capacity specifically in intelligent adolescents with HFA on a neuronal and cognitive level, as well for abstract information as for social relevant information, using neuropsychological assessments…
Primary Objective: Analyse the behavioural response of individuals with Down's syndrome directly after a painful dental stimulus and compare this with video-analysed behaviour.Secondary Objective(s): 1) Determine which observational scale can…
The Objective of this study is to validate the new developed sensor fotoplethysmografie (MPA-16), that later can be used to better understand the local vasculature. And determining the feasibility / applicability of this test setup for patients.
Our primary objective is to determine the effect of breast reconstruction on the risk of developing lymphedema. Secondarily, we will look at lymphedema and the correlation with 1) primary and secondary breast reconstruction, 2) the extent of…
The proposed study aims to evaluate the recommendations of the guideline regarding the wellbeing of the relatives according to the following questions: 1) To what extent are the recommendations of the guideline adhered to? 2) What is the effect of…
The aim of this project is to determine the possible use of biomarkers for non or delayed union in long bone fractures of the diaphyseal femur and tibia.
The objective of the study is to measure the extend of voiding symptoms and bother of the urinary tract in young females and to analyse flow patterns and post void residual.
Previous studies [10] have proposed that cartilage degeneration due to obesity could be caused by changes in the joint kinematics during ADL that shifts the loading applied to cartilage. Such a shift may cause regions of cartilage to become newly (…
Primary Objective: The main objective is to gain insight into the functional and structural neural correlates of success in foreign language learning. To this end, fMRI and DTI data will be acquired together with behavioral responses from healthy…
Primary objective: to investigate the intra- and interfraction motility of the CTV (the primary tumor as well as any affected celiac lymph nodes) in radiotherapy for esophageal cancer, and to determine adequate CTV-ITV margins.Secondary objective:…
Main: to examine how treatment response and non responder profiles relate to contemporary dichotomized forms and correlates of aggressive behaviour (i.e. pro active vs. reactive, cognitive distortions), location where the treatment is offered,…