232 results
Multi-centre open label clinical trial.
Simvastatin (an HMG-CoA reductase inhibitor) induces apoptosis in vitro and sensitizes the myeloma cell to chemotherapy. This is the first clinical trial to test if in vivo there is the same sensitization in relapse or refractory multiple myeloma.
Does lipid accumulation in skeletal muscle and the heart effect mitochondrial function in relation to insulin resistance?
Chronic sleep disorders are associated with dysfunctioning during the day. Circadian rhythm disorders are a frequently occurring cause of chronic sleep disorders. The time at which the endogenous melatonin production starts to rise plays a key-role…
Predominantly sleeping in the non-supine position could improve oxygenation and thereby shorten the disease course in admitted COVID-19 patients.
Perioperative esmolol infusion titrated for heart rate control as an add-on to standard therapy including a long acting oral beta-blocker will improve heart rate control and decrease perioperative myocardial ischemia, without an increase in…
A family involvement program will reduce the number of unplanned readmissions in adult patients undergoing major abdominal surgery.
Intrathecal methylprednisolone reduce the features of central sensitization in patients with complex regional pain syndrome type 1 having symptoms longer than 6 months and shorter than 6 years.
Children with chronical abdominal pain and small intestinal bacterial overgrowth supplemented with probiotics will show less abdominal pain compared to placebo.
1. A decrease in cocaine use over a three month period in participants who receive AAT training as opposed to VPT training. 2. A change in symptoms involving craving, the urge to use, withdrawals well as stated readiness to change in participants…
Femtosecond (FS) laser aided keratoplasty for KC is superior to MALK.
It is assumed that recurrence of appropriate ICD shocks is 30% in the Amiodarone group and 16% in the Ablation group.
The per patient annual infliximab dose can be lowered in Crohn’s disease patients in stable remission using dose reduction guided by serial trough level measurements.
Multiple rounds of S(+)-ketamine infusions will give more profound and prolonged pain relief compared to a single infusion of S(+)-ketamine.
We expect that preoperative and postoperative cooling will reduce swelling faster, reducing the time to surgery and time to discharge, respectively.
Superficial and intra-abdominal infections: 8% in the standard loop group to 4% in the endoloop closure group.
The effect of the TDM strategies on the viral load in terms of change from baseline (start or switch of therapy) to 96 weeks.
Minimally invasive pancreatoduodenectomy is as safe as open pancreatoduodenectomy
Daily use of pre-thickened oral nutritional supplements for 12 weeks will have a positive effect on body weight of older nursing home residents with dysphagia and malnutrition (risk) as compared to standard nutritional - and dysphagia management