232 results
Antipsychotics (haloperidol) can cause acute changes in cardiovascular functions, metobolic parameters and platelet aggregation in elderly patients.
Many employees who are sicklisted do not really know how to handle the situation. Simple and specific education and individually based instructions through a website can possibly solve or reduce this problem. Besides, the website contains a…
Oral ondansetron reduces the proportion of referred children to a (paediatric) emergency department when added to oral rehydration therapy compared to oral rehydration therapy alone.
Predominantly sleeping in the non-supine position could improve oxygenation and thereby shorten the disease course in admitted COVID-19 patients.
The primary objective of the study ”STOP PAIN” is to compare the effect on migraine attack frequency of transcatheter device closure of atrial shunting with a non-closure group in migraine patients suffering severe migraine with aura.
1. A decrease in cocaine use over a three month period in participants who receive AAT training as opposed to VPT training. 2. A change in symptoms involving craving, the urge to use, withdrawals well as stated readiness to change in participants…
Perioperative esmolol infusion titrated for heart rate control as an add-on to standard therapy including a long acting oral beta-blocker will improve heart rate control and decrease perioperative myocardial ischemia, without an increase in…
A family involvement program will reduce the number of unplanned readmissions in adult patients undergoing major abdominal surgery.
Half dose Urokinase (50.000IE/h) will significantly reduce hemorrhagic complications compared with the standard dose Urokinase (100.000IE/h) with comparable technical success rate
Chronic sleep disorders are associated with dysfunctioning during the day. Circadian rhythm disorders are a frequently occurring cause of chronic sleep disorders. The time at which the endogenous melatonin production starts to rise plays a key-role…
Does lipid accumulation in skeletal muscle and the heart effect mitochondrial function in relation to insulin resistance?
Multi-centre open label clinical trial.
Simvastatin (an HMG-CoA reductase inhibitor) induces apoptosis in vitro and sensitizes the myeloma cell to chemotherapy. This is the first clinical trial to test if in vivo there is the same sensitization in relapse or refractory multiple myeloma.
Intrathecal methylprednisolone reduce the features of central sensitization in patients with complex regional pain syndrome type 1 having symptoms longer than 6 months and shorter than 6 years.
Children with chronical abdominal pain and small intestinal bacterial overgrowth supplemented with probiotics will show less abdominal pain compared to placebo.
It is hypothesized that a preoperative oral antibiotic prophylaxis, that is administered in addition to perioperative intravenous prophylaxis, will lead to a reduction in postoperative would infections after colorectal surgery
Part 1 Single Ascending Dose (SAD) - To evaluate the safety and tolerability of a single oral dose of prodrug, ABX-002, in healthy adult subjects Part 2 Multiple Ascending Dose (MAD) -To evaluate the safety and tolerability of once daily oral…
Superficial and intra-abdominal infections: 8% in the standard loop group to 4% in the endoloop closure group.
Patient with incurable disseminated left-sided colonic cancer are better palliated by colonic stenting than surgery measured by hospital free survival in "good health"(WHO-score 0 or 1) Colonic stenting is cost effective in patients with…