17911 results
Intermittent neurogenic claudication due to lumbar stenosis is frequently diagnosed among older persons. Due to an aging population it is to be expected the incidence of lumbar stenosis will increase over time. Patients are operated on because of…
Our proposed randomized controlled trial is the first making this head-to-head comparison in a *real life* primary care setting in the Netherlands. The primary research question is: does a 12-week combination therapy of open label varenicline and…
The aim of the study is to understand the nutritional status of people with complex multiple disabilitiest through measurement of body composition and nutritients.The primary objective of the study is:What percentage of people with complex multiple…
Will a sleep training consisting of CBT in a chronic, psychiatric population with depressive disorder and insomnia lead to a decline of sleeping problems and a increase in sleep quality? Will the results from a normal and non chronic population will…
This study will learn us about the prevalence of asymptomatic urinary retention postpartum, as well as the natural course and complications.
To investigate if there are differences in serotonin transporters in the hypothalamus between subjects with hypopituitarism suspect for hypothalamic damage, subjects with hypopituitarism and no suspicion of hypothalamic damage and healthy age- and…
To study the effects of transient severe endogenous stress hormone exposure on the structure and functioning of brains circuitry regulating emotion, and the association with cognition and psychopathological symptoms.
The purpose of the present proposal is to improve care to children with asthma by including regular assessments of non-invasive inflammatory markers during the management of asthma. In this case, treatment is also guided by inflammatory markers (…
Primary Objective:The overall aim of the study is to examine whether the early-childhood adversities experienced by the adoptees will be transmitted to the next generation or whether the cycle of early negative experiences has been broken.Secondary…
To identify objective parameters to characterize Non Voiding Activity (NVA) in healthy and OAB subjects using high resolution urodynamic assessmentNVA are changes of pressure in the bladder lumen. These changes are measured as detrusor pressure (…
Evaluation of the rise in serum creatinine and the incidence of CIN following angiography in patients treated with a short hydration regime during 1 hour with sodium bicarbonate compared to a hydration regime with saline during 6-24 hours.
The purpose of GRN-study is: 1. to determine the long-term effectiveness of a 12 weeks lasting physical exercise training program. 2. to determine the costeffectiveness of the 12 weeks lasting physical exercise training program. In aim of the GRN-…
To determine whether increased calcium and phosphate intake (2005 group) resulted in improved Bone Mineral Content (BMC) and Bone Mineral Density (BMD) compared to the group with less calcium and phosphate intake (2004 group) at the age of 8-10…
The main goal of this project is the elucidation of the mechanism underlying the paternal inheritance seen in SDHD- and SDHAF2-related paraganglioma. The results of this project should aid us in the identification of the *modifier* gene, essential…
Main objective: To evaluate the pain reduction in patients receiving Instanyl®Secondary objectives: To evaluate; the duration of pain reduction in patients receiving Instanyl®; the degree of adverse effects in patients receiving Instanyl®: whether…
To examine whether this promising parent intervention can reduce behavioral inhibition and anxiety symptoms in Dutch behavioral inhibited children, and whether parental factors influence the treatment outcomes.
Primary Objective: To investigate the association between the weight-loss-induced cellular stress response and the rate of weight regain. Secondary Objective: To investigate the difference in cellular stress response and weight regain after rapid…
The primary objective of this study is to gain more knowledge about the mean and the distribution of mitochondrial oxygen tension (mitoPO2), the mitochondrial oxygen consumption (mitoVO2) and the affinity for oxygen of mitochondrial respiratory…
The objectives of this study are:- to evaluate the potential of dalcetrapib to reduce cardiovascular morbidity and mortality in adult patients with stable coronary heart disease (CHD), CHD risk equivalents or at elevated risk for cardiovascular…
Primary Objective: To determine the prevalence of endo- and extranasal deformities, problems with nasal functioning and satisfaction with nasal appearance in patients with TCS.Secondary Objective: To adjust and improve the treatment of patients with…