138 results
To evaluate how the 3D knee joint space distribution in knee OA patients changes under the influence of weight-bearing (upright) and flexion MRI scanning.
To examine cognition, motor function, executive functions, speech and language development, behaviour, psychosocial functioning, academic achievement, physical morbidities and growth of MLPTI at the age of 9 years and correlate this with BSID-III-NL…
The objective of the HORIZON trial is to demonstrate and provide long-term clinical data on safety and performance of the Qmedics EXIST NiTi Stent System type FLEX & PULL for treating de novo or re-stenotic symptomatic atherosclerotic…
The primary objective is to determine the survival rate after two and five years in fixed bearing Oxford lateral PKR with an uncemented femoral component and present patient reported outcome measures (PROMS), range of motion, radiographic findings…
Investigation of pelvic blood circulation by MRI in women with a gynaecological cancer who will have curative radiotherapy with or without weekly HT for inoperable pelvic tumours.
In this prospective observational study, the effects of our anticoagulation strategy during flow reduction trials will be studied. The results may help in performing safe flow reduction trials of adequate length, to be able to better decide whether…
Accordingly, this study intends to investigate the modulation of self-other processing in the psychedelic state. Specifically, the study has the following key objectives: (1) To explore the effects of psilocybin-containing truffles on self-other…
Primary Objective: To study whether the pulse oximeter functionality of the wearable ear sensor is able to reliably measure oxygen saturation, pulse rate, and respiratory rate in a clinical (postoperative) setting.Secondary Objective(s): To evaluate…
The aim of this study is to investigate potential differences in blood flow patterns, wall shear stress and energy loss in patients after mitral valve repair with the resect and respect approach.
The main objective is to examine the relationship between energy cost and (1) hip extensor and knee extensor co-activation, (2) plantar flexor and hip extensor co-activation and (3) plantar flexor and knee extensor co-activation in able-bodied…
Primary objective:To assess, in an international pediatric study, the efficacy, in terms of event-free survival, of a combination of ATO and ATRA in newly diagnosed SR APL children and adolescents and to explore the safety and efficacy of a…
This study is performed to investigate the optimal strategy for maintaining quality of life and improving survival in elderly patients (65 years or older) diagnosed with primary GBM. Primary endpoints of the study are: 1) Proportion of patients with…
Primary Objective:The primary objective is to investigate whether the retinal SpO2 - measured with invisible, NIR light - changes as a function of simulated height in the same way as the SpO2 measured with the standard finger clip.Secondary…
In this study, we therefore aim to investigate how trained immunity is systemically regulated in kidney transplant patients and how the degree of trained immunity affects graft survival in patients. A better understanding of these processes…
The primary objective of this study is to assess wall shear stress in the left ventricle outflow tract using 4D flow CMR in healthy controls, asymptomatic HCM and before and after surgical myectomy in patients with HOCM,
The aim of this study is to better understand the role of mammary lactation physiology and breast composition in regulating breast milk transfer during milk extraction. The secondary aim is to validate the performance of diffuse optical…
Primary Objective: Peri-operative change in microbiota composition between patient receiving SDD or no SDD, performed by 16S rRNA sequencing, analyzed by Microbiome Center Amsterdam (MiCA).Secondary Objective(s): 1. Correlation between the gut…
The primary objective of the current study is to investigate whether self-disgust drives food restriction in patients with AN. If this indeed is the case, this would provide important leads to improve existing treatment options for AN.
In this study, we aim to estimate genital HPV prevalences in men aged 19-27 year in the general Dutch population. Also, we aim to link the hrHPV prevalences to the HPV vaccination status after completion of the catch-up campaign to compare the…
The objective of this study is to further unravel the complexity of human milk and its variations over lactation stages and between individuals.