1093 results
The primary objective is to compare the effectivity of buprenorphine/naloxone and methadone on self-reported opioid misuse. Secondary objectives include comparing the effects on pain, well-being, functioning, and medication use.
Succes-rate of discontinuation is higher with more gradual tapering of paroxetine or venlafaxine
We hypothesise that an anti-inflammatory dietary pattern (AIDP) has a beneficial effect on gut microbiome (diversity and permeability), thereby improving global functioning (measured with Outcome Questionnaire 45, OQ-45), and health of patients with…
The primary aim of this split-mouth randomized clinical trial is to assess accuracy of bracket positioning of a fully digital IDB workflow compared to a DBB workflow, with IDB bracket planning serving as reference for both methods. The secondary…
- Six weeks of ESM combined with personalized feedback sessions, compared with treatment as usual (TAU), leads to a stronger reduction in fatigue symptoms (primary outcome clinical effectiveness). - This intervention also leads to improvements in…
To identify whether a short axis approach (SAA) or a long axis approach (LAA) to ultrasound guided peripheral cannulation is superior when performed by ED nurses without prior ultrasound experience.
Most patients undergoing spine surgery with pedicle screw instrumentation will experience insufficient pain relief in the first three days after surgery, whereafter postoperative pain can be managed with conventional, non-opioid analgesics in most…
To investigate the pharmacokinetic profile of magistrally compounded CDCA capsules.
Tones vs. neutral self-voice (EEG experiment 1 in Session 3; Pinheiro et al., 2018): a) no effect of HP on N100 suppression for self- and externally generated tones as we would expect alterations in sensory feedback only with regards to one’s own…
Patients in the intervention group will be stimulated to increase their level of PA and protein intake after hospital discharge by using multiple behavioural change techniques. Higher levels of PA and achieving protein requirements are expected to…
We hypothesize that the risk of any congenital abnormality in fetuses with an early increased NT that normalizes, will be lower than those with persistent increased NT after 11 weeks of gestation.
PENG block with phenol provides better pain relieve and mobility, and therefore quality of life, compared to current pain relieve strategies in patients with a hipfracture who are not eligible for surgery
The aim of this study is to demonstrate that a single dose of rabies vaccine can induce an equally rapid and adequate anamnestic antibody response as 3-dose PrEP to revaccination five years later.
The experimental treatment (game-supported TPM training) will contribute to a more effective generalisation of compensatory strategies to untrained tasks as compared to the active control group (CogniPlus training).
Action research in which the intervention will be developped trough short-cylce evaluation rounds by the research team together with an expert panel. The initital intervention has been designed based on scientific literature review, practical…
We hypothesise that patients in the intervention group will show a reduction in sedentary time of at least 60 minutes per day after the cardiac rehabilitation program, compared to a reduction of maximally 30 minutes per day in the control group.
The primary objective of this study is to evaluate the effect of surgical correction of pes equinovarus deformity compared to conservative treatment on personalized goal attainment. In addition, we will evaluate the effect of surgical correction of…
The primary objective of this study is to determine patient perspective of and satisfaction with follow-up type and frequency after THA and TKA. Therefore, we will send surveys to patients who had a THA or TKA between 1 and 15 years ago.
To investigate the effect of a three-week treatment with cannabidiol (CBD) on anxiety in patients with a primary brain tumor that have no active oncological treatment. Depression, fatigue and general quality of life are secondary outcome measures.…
Mainstreaming of germline genetic tests in regular healthcare is feasible for healthcare professionals and acceptable for both patients and healthcare professionals