364 results
To assess the PK/PD relationship of prednisolone regarding toxicity as clinical outcome in paediatric patients with autoimmune or autoinflammatory diseases
To demonstrate superiority of left ventricular septal pacing over right ventricular pacing and to investigate the additional effect of capturing the left bundle branch in left ventricular septal pacing (LVsP). This will be done by studying…
To assess the association between secondary brain injury in intracranial haemorrhage and the involved inflammatory response. We want to correlate perihematomal inflammation, serum inflammation markers, increased blood-brain-barrier leakage and…
To assess the potential of AT1R and ETAR antibodies to serve as a biomarkers for clinical deterioration in COVID-19.
To assess cognitive impairment in participants with highly-active RMS, having participated in the CLARIFY MS trial, at 4 years afterinitial dose of cladribine tabletsTo assess health related quality of life (HRQoL) in participants with highly-…
1. Implementation of a point-of-care fully automated analysis of neutrophils in the emergency department trauma bay in monotrauma geriatric hip fracture patients. 2. To determine if patients who develop infectious complications demonstrate decreased…
The primary objective is to measure the dose of cerebral ischemia, as a measure of cerebral hypoperfusion, before, during and after aortic arch surgery. Secondary objectives include parameters that influence the occurrence of cerebral ischemia (…
Objective: To show the protective value and to measure cost effectiveness of higher Ig dosing on progression of lung disease in PAD.
Our objective is to study SARS-CoV-2 transmission of a- and pre-symptomatic carriers during a mass gathering event with social distancing and hygiene public health measures.Secundary objectives:- To estimate the prevalence of a- and pre-symptomatic…
The main objective of this study is to perform a quality assessment on several new techniques, used in the laboratory of Translational Cancer Genomics and Proteomics
We aim to provide preliminary information on the presence of GNAQ, GNA11, RASA1 or PIK3CA gene mutations, assess the endothelial cell properties and compare it to the phenotypic characteristics of the PWSs of affected patients. This will lead to a…
Primary objective:Answering the following research questions: Does relaxation (with the help of an instruction and the biofeedback relaxation tool) compared to 'quietly lying down' result in lower activity of the pelvic floor and in a more…
The primary objective of this clinical pilot study is to explore the feasibility of Flatpanel Detector - Parenchymal Blood Volume (FD-PBV) imaging in patients with intracranial meningiomas during neurosurgery in the Hybrid-OR. Image quality, added…
The primary objective of this study is to validate the accuracy of FebriDx to discriminate between viral and/or bacterial respiratory infections. Besides this, the predictive value (negative predictive value (NPV) and positive predictive value (PPV…
Primary Objective: After ex vivo confirmation that BD injected around LC in a laryngeal surgical specimen is not spreading into tissues beyond the tumor, the detection of SLN by a technique of injecting BD via a flexible laryngoscope using a working…
To determine whether plaques in young patients with familial hypercholesterolemia (aged below 50 years) are susceptible to significant plaque regression with early, aggressive lipid lowering therapy (statins, ezetimibe and/or PCSK9) according to…
The main aim of the proposed study is to 1) assess the habitual consumption of raw cow*s milk among a large population of adult dairy farmers; 2) assess the association between raw cow*s milk consumption and inflammation-related, auto-immune and…
We aim to assess differences in the in vivo distribution of CD8+ T-cells in patients with proven SARS-CoV-2 presenting with lymphopenia or with normal lymphocyte counts, using [89Zr]Zr-Df-IAB22M2C PET/CT imaging. Elucidating the pathophysiology…
Primary objectives-To assess the concordance between [68Ga]Ga-PentixaFor PET/CT and AVS for identification and/or lateralization of APAs in patients with PA. (Step 1) -To assess non-inferiority in terms of clinical outcomes of [68Ga]Ga-PentixaFor…
Primary Objective: To analyze whether HLA-specific B-cell memory underlies rebound DSA formation, donor HLA-specific memory B-cell-derived antibodies (DSM) (IgG) will be determined before desensitization and will be associated to serum DSA rebound…