363 results
Investigate the effect of having CYP2C19 and CYP2D6 genotypes at start of antidepressant therapy and it’s cost-effectiveness in the primary care setting.
To assess the PK/PD relationship of prednisolone as either prophylaxis or therapy of GVHD in children after HCT.
Critical illness, along with the lack of zeitgebers on the PICU environment, and iatrogenic influences like medication and procedures, results in disturbed circadian rhythms in critically ill children, which is important for their recovery.
The study*s main objective is the creation and testing of a *SID Pain App* that in connection with a *smart sock* will fast and reliably detect nociceptive pain in persons with severe intellectual and motor disability (SID).
Our key objective of this study is to elucidate potential peripheral and central mechanisms that determine chronic pain characteristics in humans with OA.
Development of a laboratory assay
To assess the long-term BP lowering effect of renal denervation using a dedicated circumferential ultrasound balloon catheter in patients with resistant hypertension.
Determine the frequency, phenotype and function of disorder-related immune cells, or levels of immune molecules in skin and peripheral blood of patients with inflammatory skin diseases, during the active phase of disease prior to and/or at any time…
The primary objective of the study is to compare the ADR between PCSC and CC in patients referred for diagnostic, screening (non-iFOBT based) or surveillance colonoscopy.Secondary objectives are the following:- To compare the polyp detection rate (…
The goal is to get a better understanding about the role of innate immune cells and the development of ASCVD in obese subjects. We will look at the innate immune cells in blood and at the progenitor cells derived from the bonemarrow.
To investigate the dynamics of IgA and IgG antibody level against SARS-CoV-2 in 86 health care workers with relatively mild symptoms.
(Refer to Protocol Section 2)Primary Objectives* To establish an in vitro assay to study recognition and killing of P. falciparum-infected hepatocytes by:o CSP-specific cytolytic CD8+ T cellso hepatic and peripheral innate/innate-like…
We want to show in the current pilot trial that the current market ready automated device is safe and effective to use in humans as the proof of principle prototype, as well as check the instructions for use (IFU).
The goal of this study is to investigate whether BOLD MRI can predict the occurrence of buttock claudication after coiling of the internal iliac arty. The BOLD technique will be used to measure blood supply parameters of the gluteal muscle during…
To investigate the changes in the skin immune system after 12 weeks of biologic therapy treatment in patients with HS.
The aim of this study was to test these biomarkers of NO in glaucoma patients both with and without tinnitus. The objective was also to replicate findings from a previous study performed in Amsterdam, a collaboration between our research group and…
The primary objective is to study the association between maternal TL and the risk of SB in offspring. The secondary objectives are to investigate the relation between maternal TL and obstetrical (pregnancy course and outcome), environmental risk…
The primary objective of this study is to investigate the sequence of segmental contributions in the cervical spine in the long-term follow-up of surgery for CDDD. Specifically, the motion of the cervical spine after ACD and ACDA will be analyzed…
The primary objective of this study is to assess the diagnostic accuracy, in terms of sensitivity and negative predictive value, of preoperative CT lymphography as compared with conventional lymphoscintigraphy for SLN detection. Secondly, we aim to…
To determine the difference in change over time of cognitive function and brain magnetic resonance imaging (MRI) measurements between breast cancer survivors and cancer-free individuals.