651 results
Quantification of mast cell density in human volunteers will inform future interventional studies that impact mast cell proliferation and/or turnover
The hypothesis is that patients with low anti-TNF drug levels have a higher risk of loss-of-response to anti-TNF drugs compared to patients with high anti-TNF drug levels.
We hypothesize that an evidence based diagnostic algorithm, using fewer and preferably the least invasive diagnostic modalities can approach the accuracy of the complete panel of diagnostic tests.
We hypothesize that medical nutrition (PN and EN) compared with no medical nutrition (only oral nutrition) will be associated with better maintenance of nutritional status (fat- and fat free (muscle) mass and body weight), functional capacity,…
The natural experiment of COVID-19 related governmental measures of home confinement and social distancing has led to a decrease in physical activity levels of school going adolescents of Punjab, India.
We expect that planned visits at the outpatient clinic are unnecessary due to low percentage of treatment changes. Furthermore, we expect that treatment changes will appear at unplanned visits.
The level of AGEs can predict response to intravitreal anti-VEGF therapy in DME
We expect the protein synthesis rate in (avascular) femoral bone proximal to the fracture to be lower when compared to healthy femoral bone.
Doctors exposed to aerosol generating procedures (AGP) are more at risk of contracting COVID-19 than those not exposed to AGP
To evaluate clinical outcome, 30-day mortality, 5 year mortality and related costs of elderly burn patients in specialized burn care. To evaluate factors related to poor outcome, including12-months mortality, discharge destination and 30 days…
Satisfying results for both groups of patients, non-inferiority
We hypothesize that several parameters, measured with a wrist-worn data logger, will be predictive for a heart failure event. Parameters which are taken into account are: heart rate, activity count, energy expenditure, but also parameters which are…
We hypothesize that tumor ex vivo radiosensitivity correlates with clinical response to (chemo/bio-)radiotherapy in vivo. The manner of relation will be assessed in this study. Moreover, we postulate that establishing a biobank of OPC tumor and…
Active surveillance is a reasonable treatment option for selected ALT patients
Severity of insomnia at three months post-stroke is correlated with severity levels of post-stroke depression.
Combined pressure-flow measurements under hyperaemia can identify those patients with renal artery stenosis that will benefit from renal revascularization, assessed by blood pressure and renal function. The hemodynamical significance of a renal…
It is expected that Covid-19 patients, whose symptoms are considered as "mild" (i.e., who have not usually been hospitalized) can experience prolonged complaints, resulting in reduced quality of life.
We hypothesise that Endocytoscopy is feasible to detect dysplasia/carcinoma in patients with BE
Low frequency stimulation causes vasodilation in the affected extremity of patients with CRPS
In advanced stages, vascular reconstructive surgery with the use of venous patch may be indicated. If the disease is detected at an earlier stage, less invasive surgical treatment, consisting of release of the iliac artery, is possible and it might…