104 results
Investigate anatomy, kinematics, clinical outcomes, and functional outcomes in Madelung deformity patients.In this study we will answer the following 3 questions:1) What is the anatomical situation of the wrist in patients with Madelung deformity,…
Taken together, social performance monitoring processes and empathic abilities are key ingredients for efficient social behavior. Possible disturbances in these processes may severely inhibit or even impair social interactions with possible long-…
The primary objective of this study is to evaluate the safety and feasibility of 3 months martial arts based training program for DMD patients. The secondary objective is to gain a first impression on the program*s ability to optimally use one*s…
We aim to prevent or reverse developmental regression in patients with Kleefstra syndrome. We hypothesise that the regression we observed is the result of a psychotic disorder, which isnot properly recognised by clinicians and often not treated…
The objectives are firstly that Love is... promotes the healthy sexual development by increasing knowledge and positive attitudes towards sexuality. Secondly, characteristics of adolescents who do not improve from the general prevention program are…
The effect of mebeverine on abdominal pain intensity and frequency in children with irritable bowel syndrome or functional abdominal pain – not otherwise specified will be effective.
Point of care testing with Fcal POCT will reduce substantial the referral rate of children with chronic GI symptoms to the paediatrician.
The aim of the Continuous versus Intermittent Nutrition in Pediatric Intensive Care randomized controlled trial (RCT) is to investigate a strategy of intermittent nutrition with a focus on an overnight feeding interruption period versus 24-hour…
This multicentre randomised controlled trial aims to investigate whether PoCUS can be used as an adjunct to improve first attempt success rate in closed reductions of displaced distal radial fractures in adults in the ED.
Primary Objectives: -To evaluate if the treatment of Low Risk HB can be reduced (Group B1) -To compare different induction treatment regimens for Intermediate risk HB (Group C) -To compare different post induction treatment regimens for…
REE will be assessed using indirect calorimetry. Oxygen consumption (VO₂) and carbon dioxide production (VCO₂) will be measured. The respiratory quotient (RQ) will be derived from VO₂ and VCO₂. Body composition will be determined by…
Smell and taste function change during chemotherapy consequently affecting 1) dietary intake 2) eating behavior 3) anthropometry 4) quality of life
The standard-of-care sentinel lymph node (SLN) procedure in paediatric cancer patients consists of a preoperative intradermal injection with 99mTechnetium-nanocolloid as radiotracer in combination with an intraoperative injection of blue dye for…
The objective of the study is to set up and validate a digital neurotraumatology quality registry, to identify the most effective clinical care and to provide high quality evidence in support of treatment recommendations and guidelines.
This study aims to gain clarity on the issue of treatment for clinical levels of social anxiety in adolescents by testing the effectiveness of a group-based intervention. Most importantly, it aims to research the effectiveness of an added mHealth…
- To investigate the long-term outcome of the intervention strategy for FGR (induction of labour) that is worldwide applied after the original DIGITAT study, in relation to induction of labour versus expectant management.- To investigate…
Main objectives are:1. To explore differences in cerebral perfusion and flow pulsatility between CoA patients and controls.2. To quantify ischemic white matter lesions and cerebral microbleeds in CoA patients with comparison to controls.Secondary…
This study will evaluate the safety, efficacy, pharmacokinetics, and pharmacodynamics of emicizumab in patients of all ages with mild (FVIII level between > 5% and < 40%) or moderate hemophilia A (FVIII level between >= 1% and…
Our research aims to establish informative tools in the laboratory for studying the molecular and cellular pathways that are altered in SETBP1 disorder.
The main research objectives for the proof-of-concept study are to show the feasibility and safety of a daily cycle of feeding and fasting in critically ill children of different age-groups, that will trigger an adequate fasting response while…