137 results
Investigate anatomy, kinematics, clinical outcomes, and functional outcomes in Madelung deformity patients.In this study we will answer the following 3 questions:1) What is the anatomical situation of the wrist in patients with Madelung deformity,…
Taken together, social performance monitoring processes and empathic abilities are key ingredients for efficient social behavior. Possible disturbances in these processes may severely inhibit or even impair social interactions with possible long-…
The primary objective of this study is to evaluate the safety and feasibility of 3 months martial arts based training program for DMD patients. The secondary objective is to gain a first impression on the program*s ability to optimally use one*s…
We aim to prevent or reverse developmental regression in patients with Kleefstra syndrome. We hypothesise that the regression we observed is the result of a psychotic disorder, which isnot properly recognised by clinicians and often not treated…
The objectives are firstly that Love is... promotes the healthy sexual development by increasing knowledge and positive attitudes towards sexuality. Secondly, characteristics of adolescents who do not improve from the general prevention program are…
The effect of mebeverine on abdominal pain intensity and frequency in children with irritable bowel syndrome or functional abdominal pain – not otherwise specified will be effective.
Point of care testing with Fcal POCT will reduce substantial the referral rate of children with chronic GI symptoms to the paediatrician.
The aim of the Continuous versus Intermittent Nutrition in Pediatric Intensive Care randomized controlled trial (RCT) is to investigate a strategy of intermittent nutrition with a focus on an overnight feeding interruption period versus 24-hour…
Primary Objectives: -To evaluate if the treatment of Low Risk HB can be reduced (Group B1) -To compare different induction treatment regimens for Intermediate risk HB (Group C) -To compare different post induction treatment regimens for…
REE will be assessed using indirect calorimetry. Oxygen consumption (VO₂) and carbon dioxide production (VCO₂) will be measured. The respiratory quotient (RQ) will be derived from VO₂ and VCO₂. Body composition will be determined by…
Smell and taste function change during chemotherapy consequently affecting 1) dietary intake 2) eating behavior 3) anthropometry 4) quality of life
The standard-of-care sentinel lymph node (SLN) procedure in paediatric cancer patients consists of a preoperative intradermal injection with 99mTechnetium-nanocolloid as radiotracer in combination with an intraoperative injection of blue dye for…
The objective of the study is to set up and validate a digital neurotraumatology quality registry, to identify the most effective clinical care and to provide high quality evidence in support of treatment recommendations and guidelines.
To investigate the role of talkers* voices in speech communication in NH, HI, and CI children and adult listeners, and how the perception of talker voice information relates to the processing of indexical and linguistic information among these…
Primary Objective:To measure the efficacy provided by nivolumab therapy on its own compared to placebo in participants who have had their stage IIB/C cancer completely removed, and have no evidence of disease, but are at high risk of recurrence.…
To initiate a Dutch cohort with standardized follow-up measures and investigating blood, liquor, urine samples and nailfold videocapillaroscopy findings for prognostic factors during disease quiescence and at times of disease flare. This will…
The main objective of this study is:This study investigates whether diagnosis and treatment of challenging behaviour, as provided by an specialist team of mental health care professionals and intellectual disability professionals, when optimising…
To study the differences in MI between short-term ill adolescents with AN (< illness duration 1 year) and patients who started their illness in adolescence and have been ill for at least 5 years consecutively and with healthy controls. A…
Despite seeing an increase in children admitted to the paediatric intensive care unit for severe acute asthma, we still do not know what the cause of this increase is, and we still only have few drugs we can give these children, regardless of the…
The primary objective is to assess the efficacy of etrasimod when administered for 12 weeks on clinical remission in subjects with moderately to severely active ulcerative colitis (UC). The secondary objective is to assess the efficacy of etrasimod…