4707 results
The association between the gut microbiome/virome, T-cell exhaustion and immuno-tolerance in T1D constitutes an important knowledge gap and may serve as a therapeutic target in T1D, that will be adressed in this cohort study.
In chronically agrammatic speakers of Dutch, SimpTell leads to an enhancement of elliptical style which in turn improves verbal functional communication, specifically verbal efficiency.
We hypothesize that the use of oral estradiol is effective in women with irregular bleeding with a LNG-IUS in situ for more than 6 months
Primarily, we expect that the use of biofeedback will have beneficial effects on transfer to real-life situations, resulting in a decrease of intimate partner violence from pretest to posttest. Secondly, we hypothesized that biofeedback will…
We hypothesize that the incidence rate of contralateral lymph node metastases in patients with lateralized oral cavity squamous cell carcinoma, clinical ipsilateral metastases and a contralateral clinically negative neck is equal or higher than…
We hypothesize that sleep apnea screening, using a combination of an online questionnaire and high resolution overnight oximetry, can safely be applied to exclude sleep apnea with high sensitivity (≥97%) and acceptable specificity (≥60%) in patients…
Our hypothesis is that the ratio omalizumab trough-level to baseline IgE differs from the 15:1 ratio, which was found to induce adequate asthma-suppression in early trials. The patients yearn for the next gift may be associated with an inadequate…
Sarilumab reduces PD severity in RA patients with PD
The intended research aims to evaluate whether a better suppression of adrenal androgens, so a better hormonal setting, can be achieved by changing the time of the highest dose in the morning or in the evening.
This study will provide in-depth insights into the nutritional status and intake of school aged children (6-12 years old) and women of reproductive age (WRA) (15-49 years old) in Ivory Coast
Our hypothesis is that less meat will be purchased in the meat tax condition, the information condition and in the combined condition (tax and information condition) compared to the control condition. We expect the largest reduction in meat…
Epidural analgesia is superior to placebo in reducing post-operative pain.
Image-guided navigation surgery allows the optimal use and full integration of pre-operative images during surgical procedure. This feasibility study investigates the potential of this new technique in surgery in rectal surgery. The hypothesis is…
Metformin has antineoplastic activity but thus far has not shown clinical benefit in the treatment of cancer in humans. Metformin is excreted by the kidneys and accumulates unchanged in the urine where, compared to serum, it reaches a 240-fold…
A priori, we hypothesize that fatigue is highly prevalent in patients with chronic diseases and little is known on effective treatment strategies to reduce fatigue.
Total laparoscopic hysterectomy is equally safe with respect to five-years disease-free survival outcomes in comparison to a total abdominal hysterectomy
We hypothesize that suppression of the gonadal axis will increase bone marrow and visceral fat in biological women and men and subsequent administration of estradiol or testosterone will decrease the amount of bone marrow and visceral fat. We…
The aim of the present prospective cohort study is to assess the clinical and microbiological effects and patient-reported pain in the non-surgical treatment of peri-implantitis using a pocket irrigator/evacuator device
Several weeks of home monitoring of blood oxygen levels of patients with or at risk of cardiovascular disease with moderate to severe symptoms of (presumably) COVID-19 by pulse oximetry might benefit the patient by early detection of hypoxemia, an…
We are interested in the workability of the non-invasive abdominal electrode patch for implementation in clinical practice. We expect to establish a reduction of use of fetal scalp electrode from 70% to 45%. Postpartum monitoring of contractions…