765 results
PVAT plays an important role in driving vascular ageing manifested by medial smooth muscle cell (SMC) dedifferentiation into an osteogenic phenotype that induces intimal and/or medial calcification. I furthermore hypothesize that this process of…
Microstructured BCP might be a suitable substitute to autologous bone graft in the sinus floor augmentation procedure
Aim of the MANCO study is to establish for once and for all that monitoring the effect of heparin during NCVI is essential to ensure the individual patient of safe and tailor-made anticoagulation. Not measuring the effect of the administered heparin…
It is hopthesized that a multidimensional implementation approach with multiple interventions integrated in the usual care will improve physical behaviour during hospitalization
The reported incidence of dysphagia in multiple sclerosis (MS) varies between 33% and 90% and is higher in more disabled patients. Dysphagia is associated with an increased risk of aspiration pneumonia, increase in health-care cost and increase in…
IPA as first-line therapy in the Emergency Department leads to: - faster initiation of symptomatic treatment for nauseous patients - more patients receiving symptomatic treatment for nausea - a decrease in the use of conventional anti-emetics - a…
Two-stage implant-based breast reconstruction is the most common reconstructive technique after mastectomy. It is associated with some implant specific complications such as capsular contracture. Capsular contracture is one of the most frequent long…
Is there a significant difference in Anterior/Posterior stability between MRK, LCS and NexGen total knee prosthesis 1 year post-op?
1) There will be an effect of anodal stimulation to the left STG with reduced response bias on the signal detection task 2) This effect is specific for speech signal detection.
In this project, a personalized EMA and feedback module, named Therap-i, is added to the treatment-as-usual (TAU) in patients with a depression diagnosis in tertiary care. The module is used to systematically self-monitor and reflect on momentary…
To test the safety and preliminary efficacy of a dual acute thrombolytic treatment consisting of a small intravenous (IV) bolus of alteplase followed by IV infusion of HisproUK against usual treatment with IV alteplase in patients presenting with…
The primary objective of this clinical trial is to obtain pilot safety and efficacy data on treatment of PAH patients by 6-MP. The secondary objective of this clinical trial is to determine whether LEPs transcriptome analysis will identify a subset…
Use of gamma-hydroxybutyrate (GHB) can lead to severe dependence or addiction. Patients often relapse in GHB use after detoxification. NISPA, Trimbos Institute and Bonger Institute are developing an instruction guide for relapse management. A…
Patients with good outcome in terms of motor functioning and communication are likely to be discharged home without referral to further rehabilitation services. A substantial amount of these patients experience emotional and cognitive problems,…
- The intervention prevents decline in Quality of Life (primary outcome), perceived stress and communication in the relationship in PwD, as compared to before the intervention? - The caregiver has improved self-efficacy (primary outcome) and…
This study will allow us to define the optimal dosis and value of these HPV DNA vaccines for the treatment of HPV16+ (pre)malignancies.
There is a possibility that the Philadelphia neck collar gives better results than the stifneck collar on the proposed outcomes.
Albendazole could be a novel therapeutic agent for anti-TNF alpha combination therapy in patients with Crohn's disease
The objective of the study is to determine whether optical measurements can support pulse detection during cardiopulmonary resuscitation. The optical measurements will be compared with standard measurements such as palpation,…