2398 results
The main objective is to investigate the additional value of CRP-POCT (C-reactive protein point-of-care-test) testing in patients suspected of airway infections in long-term care facilities.
The purpose of this investigation is to evaluate decellularized homograft for aortic valve replacement (ARISE AV) rates in comparison to current valve substitutes within a large prospective multicentre surveillance at 6 leading European Centres for…
The objectives of this study are to evaluate the safety and performance of the valve and delivery systems for the treatment of symptomatic moderate to severe degenerative or functional mitral regurgitation in a prohibitively high risk patient…
Biobanking of testicular biopsies from azoospermic men undergoing testicular sperm extraction (TESE)
Biobanking of a testis biopsy from men with azoospermia who undergo a TESE procedure to allow investigation for understanding the etiology of male infertility, research about normal and aberrant male gamete formation in its natural environment of…
In this study we use a unique paradigm which can be used to examine both high-level (serial dependence) effects as low-level (adaptation) effects. By doing so we hope to resolve the discrepancy in the previous findings. We expect that low-level…
The main objective of this study is to develop a PDT and salvage surgery combination specific for recurrent or residual tumors of the sinonasal cavities, unsuitable for the conventional treatments like radical surgery or radiotherapy with curative…
Area of interest (study setting): Specific aims:Transient triggers and chronic riskfactors (case-crossover and casecontrol)(1) To investigate frequency and strength of association between transient physical andpsychological triggers and early-onset…
Is the performance on pretreatment exposure, assessed by the BAT-procedure, related to symptom change after 12 weeks of specialized clinical CBT, in patients with Obsessive-Compulsive Disorder?
Objective: To evaluate the adherence of patient*s use of OS.
Primary Objective: to explore the feasibility and to identify potential hurdles of in vivo assessment of pigmented skin lesions by Raman spectroscopy.Secondary Objective(s): - to compare in vivo measurements with the results obtained by ex vivo…
The objective of the study can be defined into two goals1. Reduction of CIN using the Renalguard with furosemide forced diuresis in patients known with chronic kidney failure whom require an endovascular intervention of the lower limbs. 2. Early…
To obtain a comprehensive overview of long-term (*5 years after burn injury) consequences after burn injuries, both in all patients admitted to burn centre admissions and in a subgroup of patients who suffered from more extensive burns.
To validate MRI for assessing craniocaudal tumor extension with histopathology using non-rigid egistration. In addition to 3 Tesla magnetic resonance T2-weighted imaging, diffusion weighted imaging (DWI) and dynamic contrast enhanced (DCE) imaging…
To investigate whether long-term activation of the innate immune system, named *trained innate immunity*, occurs at the level of the bone marrow progenitor cells in patients with significant coronary artery disease and whether this correlates with…
Study I aims to explore dysregulation of biological stress systems among traumatized youths with and without ID in residential care, and compare them with a healthy control group. Study II aims to conduct a randomized controlled trial (RCT) to test…
To investigate the long term (ten years) protective immune response to fractional yellow fever vaccination (1/5th of the standard dose, injected intradermally), compared to the standard subcutaneous vaccination
The following research questions will be addressed in two different studies:1. Do addicted patients with high scores on psychopathy have reduced empathic concern associated with reduced LPP amplitude and mu-suppression during an empathy task? 2. Are…
To compare acylated and unacylated ghrelin concentrations in pregnant women with GD and without GD.
The aim of our project is to perform a novel mass screening to detect CD in 12 months-4 years old children who visit the YHCCs in a well-described region in the Netherlands, to show that it is feasible, efficient, cost-effective and well accepted by…
The main objective is to compare the efficacy and safety of esophageal dilation with the balloon the Savary bougie dilator according to the rule-of-3 to rule-of > 3 strategy during 6 months in patients with a severe benign esophageal…