1558 results
The aim of the proposed study is to examine the effectiveness of this new form of attentional bias training as an add-on to treatment-as-usual in facilitating abstinence from alcohol use in patients diagnosed with alcohol dependence. Additionally,…
Primary objectives:1) To evaluate the safety of four different CHMI-trans protocols in healthy malaria-naïve volunteers challenged with Plasmodium falciparum by sporozoite challenge. 2) To determine the best CHMI-trans protocol for induction of…
The main objective of this study is to determine the release profile of the dexamphetamine sustained release tablets in vivo in humans. Depending on the results, the tablets might be candidates for use in the therapy of attention deficit…
Primary Objective:-Evaluate tumour detection sensitivity and specificity with the following image enhancement modalities:1 *narrow-band imaging*, (NBI)2 *near-infrared indocyanin green imaging*, (ICG)3 *5-aminolevulinic acid fluorescent imaging*, (5…
To assess functional outcome and using gait analysis to quantify kinematic and kinetic abnormalities of servicemen who suffered foot injuries due to combat actions.
First we want to determine whether early high protein intake, using an enteral whey protein supplement, in addition to a standardized exercise training program and standard enteral nutrition preserves: a) in vitro skeletal muscle function in…
To analyze the percentage of HCA becoming hypointens 20-25-30-35-40-45 minutes after IV contrast injection of gadobenate dimeglumine.
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The primary objective of this confirmatory study is to confirm the acid neutralisation action of Gaviscon Double Action Liquid versus placebo liquid, within the stomach.
Considering the lack of consensus, we feel these mechanisms merit additional focus and research. LD transfer changes shoulder anatomy and thus affects the complex interplay in the glenohumeral and scapulothoracic joints. So far, no study has been…
Original study:The goal of this study is to have a theoretically based understanding of how sub processes of self-concept development emerge in relation to each other. The primary objective is to test a neuroscientific model of self-concept…
The objective of the LEOPARD-2 trial is to assess the safety of MIPD versus OPD and after that to assess the time to functional recovery of MIPD versus OPD for symptomatic benign, premalignant or malignant peri-ampullary disease.
The main goal of this phase II study is to investigate whether a focal ablative SBRT boost to the macroscopic tumor is feasible and associated with acceptable toxicity in addition to whole gland prostate SBRT. Based on the present study, a phase III…
The purpose of the study is to investigate wether long-term resveratrol supplementation (6 months) leads to improved insulin sensitivity (estimated by Matsuda Index) in people with overweight/obesity. In addition we will investigate effects of…
Part I Preclinical study using the VIRTUAL preclinical prototype Primary objective:- To validate the reliability and applicability of regular use of the VIRTUAL (pre)clinical prototype in a bed-side setting (desktop) preconceptional and across…
Safety (Primary) ObjectiveThe primary objective for this study is as follows:- To evaluate the safety and tolerability of cobimetinib in children and young adults, including estimation of the maximum-tolerated dose (MTD) or the maximum administered…
The UPGRADE-RT trial will investigate whether de-escalation of the elective radiation dose and introduction of an intermediate dose-level in the treatment of head and neck cancer will results in less radiation sequelae and improved quality of life…
To study the effectiveness of the PhysioDom HDIM intervention in maintaining or improving nutritional status and quality of life. Furthermore, the effects on behavioural determinants, appetite, dietary intake, weight, physical activity, and physical…
To gain further insight into the interaction and possibly shared pathophysiological mechanisms of female-specific cardiovascular risk factors and events we will quantify white matter hyperintensities on brain MRI and assess endothelial function in…
What is the prevalence of gastro-intestinal disorders and which are the determinants?