555 results
The main objective is to examine the change in 68Ga-exendin tracer accumulation in the pancreas (i.e. beta cell mass) after RYGB by quantitative analysis of PET images before and one year after RYGB in morbid obese patients with type 2 diabetes.
1. To assess the feasibility of SLN identification in endometrial cancer.2. To examine in how many cases SLN biopsy provides results that will tailor adjuvant treatment3. To investigate if SLN biopsy in women with low- and intermediate-risk…
The primary goal of this study is to assess the feasibility and acceptability of the worry reduction intervention among MUS-patients and GPs as implemented in primary care. A second important goal of this study is to assess the feasibility of…
The primary objective of this study is:- To determine the potential difference in MT and RNFLT between treated and untreated patients with anisometropic or strabismic amblyopia. Secondary objectives are:- To determine the potential differences in MT…
Objective: The purpose of this study is to compare the diagnostic surgical rate of a matched control group, derived from a retrospective review of patients without GEC testing, with a prospective GEC tested group.
Primary objectiveTo assess the risk of breast cancer relapse associated with temporaryinterruption of endocrine therapy (ET) to permit pregnancy.Secondary objectiveTo evaluate factors associated with pregnancy success after interruption ofendocrine…
To assess safety and tolerability of EA-230 in patients undergoing cardiac surgery with cardiopulmonary bypass.To assess the anti-inflammatory effects of EA-230 in patients with systemic inflammation following cardiac surgery. To assess the effects…
There are two objectives for this study: first, to find specific serum beta cell damage markers that can serve as a clinical predictive tool for beta cell allograft loss. Second, to compare quality of life and diabetes-related outcomes in patients…
The primary objective is to obtain OCT data for children aged 4 to 10 diagnosed with non-syndromic craniosynostosis and to compare these to the normal reference values.
Primary: To explore the diagnostic value to distinguish PAF and MSA of a variety of tests: corneal confocal microscopy optical coherence tomography (OCT) to measure the retinal nerve fibre layer thickness and total macular volume, corneal…
To systematically unravel the complex victimhood of refugee mothers and their children, and to discern whether children born from sexual violence face even greater challenges. This information will be used to develop resources for professionals…
To investigate whether bright light therapy is an effective treatment for depression during pregnancy compared with low-intensity placebo light therapy (proof-of-principle) and to investigate the late effects of bright light therapy versus placebo…
The primary objective of this study is to assess reasonable safety and performance of the HeartMate PHP to provide hemodynamic support for up to 72 hours in patients with cardiogenic shock requiring stabilization.
The overall aim of the study is to improve diagnostic and therapeutic options for people with CF, especially in the context of young children and novel CFTR-targeting drugs. Primary Objective: 1. to demonstrate relations between CFTR genotype,…
The proposed study will further examine the effects of pregnancy on the human brain, by investigating structural and functional connectivity, local metabolite concentrations and neural activity related to social cognitive and memory processes.…
Primary Objective:First we need to establish that patients with an eating disorder and healthy controls differ in mental imagery. So, the first aim of our research is to compare the nature and characteristics (emotionality, vividness and perspective…
To study the role of brain metabolites and macromolecules in relationship to pathogenesis, structural brain changes and clinical phenotype of ALS. This will reveal underlying molecular mechanisms of pathogenesis, structural brain changes and…
Our primary objective is to investigate the effects of methylphenidate on language comprehension and creativity, and to link these effects with the effects of methylphenidate on working memory. Our secondary objective is to establish the relation…
To determine the vaginal microbiota composition during preeclampsia
Primary objective: to determine the incidence and location of thrombi in the umbilical venous catheter route during and after umbilical catheterization and in the same route in infants without umbilical catheters. Secondary objectives:A. to…