332 results
Primary objectiveTo assess whether the use of alimemazine improves symptoms of allergic diseases and ADHD, as scored by the parents using standardized questionnaires (Sample Snap IV rating scales)
The first aim of this study is to examine differences in implicit and explicit learning in children born very preterm. The second aim is to test the alleged role of working memory and attention on (explicit) motor skill learning in preterm children…
The primary objective is to obtain OCT data for children aged 4 to 10 diagnosed with non-syndromic craniosynostosis and to compare these to the normal reference values.
The aim of this proposal is threefold: (i) test a neuroscientific model of prosocial development by relating neuroscience discoveries to changes in several dimensions of prosocial development in a comprehensive study including children, adolescents…
In this study, the aim is to perform a clinical evaluation of the NovioMini in children during behavioural bladder training to examine the performance of the NovioMini as a full-bladder-based notification system during natural bladder filling.
The primary objective of the proposed study is to investigate whether bumetanide therapy indeed reduces autistic symptomatology. Important secondary goals of this project are to determine whether bumetanide will improve specific behavioral,…
To establish a healthy control group for microcirculatory parameters for current and future studies on the paediatric microcirculation.
To compare gait and balance measured by the traditional 3D gait analysis system (VICON) and by the new system including a treadmill and a virtual environment (CAREN) during self- paced walking in typically developed children. In addition, a…
Monitoring and evaluation of the Dutch guideline for treatment of aHUS in children and adults during two years.
Primary Objective:To evaluate the effect and sustainability over time of behavioural treatment for sleep problems in children with AS on the actual hours of sleep and sleep behaviour of the children.Secondary Objectives:To evaluate the effect and…
To determine whether administration of exogenous surfactant using a minimally-invasive technique improves outcome in preterm infants 25-28 weeks gestation treated with continuous positive airway pressure (CPAP).
We hypothesize that functional brain network measures may serve as a marker for (disrupted) neurodevelopment in very preterm born infants. Objective: we propose to perform two studies aiming to answer the following questions.Phase 1: Retrospective…
This research project aims to determine the feasibility of setting up a randomized controlled trial to study the effects of different fluid management protocols on the outcome of mechanically ventilated pediatric patients with acute infectious lung…
Primary Objective: The main objective is to investigate the effectiveness of PRT compared to CAU in school-aged children and adolescents with ASD.The primary research question is:1) Directly after treatment and at follow-up, what is the…
To assess fidelity (quality), dose delivered (completeness), dose received (exposure and satisfaction), recruitment and context of two newly developed upper limb home-based training programs, i.e. one based on implicit strategies and one based on…
Original study:The goal of this study is to have a theoretically based understanding of how sub processes of self-concept development emerge in relation to each other. The primary objective is to test a neuroscientific model of self-concept…
To study wether a biodressing impregnated with polyhexamethylene biguanide in the treatment of spoke injuries in children could give a reduction in pain during the treatment compared to the standard treatment with wound dressing impregnated with
Primary Objective: To prospectively assess the impact and relevance of several risk factors for SAA/acute wheeze that have been identified in retrospective studies, including our own. Secondary Objective: To assess short-term medical and…
Safety (Primary) ObjectiveThe primary objective for this study is as follows:- To evaluate the safety and tolerability of cobimetinib in children and young adults, including estimation of the maximum-tolerated dose (MTD) or the maximum administered…
To systematically unravel the complex victimhood of refugee mothers and their children, and to discern whether children born from sexual violence face even greater challenges. This information will be used to develop resources for professionals…