4678 results
We hypothesize that depletion of carnitine occurs during infusion of oxaliplatin, due to increased renal loss. This secondary carnitine deficiency may contribute to the development of CIPN.
The administration of propranolol will inhibit the increase in dermal blood flow (DBF) induced by capsaicin application.
We hypothesise that the diet over time has become healthier and more sustainable. Our current study was set up to (1) identify the differences in food consumption and nutritional quality over the course of 20 years in the Netherlands using the…
It is hypothesised that compared to waiting list control condition, participants in the intervention improve their diet and physical activity on the short (6 months after baseline) and long-term (12 months after baseline; when the participant…
this study hypotheses that EEG does not predict future seizures. If correct abandoning routinely EEG will lead to a reduction in health costs and patient/family burden. Furthermore, neurocognitive development will be investigated two years after…
Our hypothesis is that piperacillin/tazobactam, ciprofloxacin, co-trimoxazole and doxycycline are able to penetrate hepatic cysts.
The study of determinants of cardiovascular disease (CVD) is important because it provides insight in risks and opportunities to reduce the burden of CVD. A major gap in our current knowledge about CVD lies in the way we measure these determinants,…
The guided internet-based behavioral activation intervention is expected to show favorable effects in comparison to online-delivered minimal psychoeducation without support in participants with depressive disorders, as shown by the results on…
Het doel van de studie is om op de consultatiebureaus in de regio Kennemerland de haalbaarheid, kosten-effectiviteit en acceptatie van vroege opsporing naar coeliakie (door middel van case finding) bij kinderen tussen de 12 maanden en 4 jaar te…
Changing the context in which individuals make lifestyle choices has a sustained impact on the dietary intake and cardiometabolic health.
We aim to study the use of braces for thoracolumbar burstfractures, not only by measuring the functional scores and the effect of the bracing or functional treatment on the increase in kyphosis angle, but also on (health related) quality of life and…
Treatment with rhEPO has no effects on performance parameters measures by exercise tests.
The constantly increasing number of aorto-iliac lesions in patients with end-stage renal disease (ESRD) seems to be the result of three main factors: increased recipient age, frequent atherosclerosis accompanying with end-stage renal disease and…
Submucosal irrigation with the Gum Irrigator will reduce bleeding on probing, pocketdepts and the amount of anearobic bacteria in the non-surgical treatment of peri-implantitis.
Food provision does not match food consumption. The amount of protein in consumed hospital meals is below current protein requirements.
It is important that parents quit smoking, as this has serious detrimental effects on their own health and their children's health. The majority of parents want to quit smoking. However, many quit attemts are unsuccessful. Recently a proactive…
Inflammatory Bowel Disease patients using thiopurines are at higher risk of developing liver abnormalities than IBD patients without thiopurine exposure.
- It is hypothesized that a tailored, outreaching and systemic intervention promotes medication adherence - It is hypothesized that a tailored, outreaching and systemic intervention has a beneficiary effect on other medical as well as psychological…
We want to determine the influence and safety of probenecid on sorafenib pharmacokinetics. By inhibiting the OAT6 transporter there might be a faborable effect on Hand-foot syndrome
(Experimental) participants who receive information about the availability and use of mindfulness-apps after an MBSR course: (1) report higher frequency of mindfulness practice, (2) report higher mindfulness, lower general psychopathology, and…