4781 results
The purpose of the study is to evaluate the usability of PatientCoach by patients with asthma and/ or COPD,hypertension and/or Diabetes Mellitus.
Primary objective of the study is to determine the effect of 2 different treatment strategies of vitamin D supplementation on 25(OH)D3 serum concentration after 12 months of supplementation. Secondary objectives are to determine the effects on the…
To monitor the systemic effects of radiotherapy (RT) alone or in combination with concurrent chemotherapy (CRT) (Cisplatin) on the immune response and T-cells over time in patients with HPV+ head and neck squamous cell carcinoma (HNSCC).
Aim1. To investigate the long-term effects of early detection and intervention of hearing loss on the development of children with congenital bilateral hearing impairment. 2. To define factors in early childhood that are able to predict…
This study is part of a prospective cohort study in the University Medical Center Groningen aimed at the determination of prognostic factors for outcome of children with TBI. The study is a pilot study to determine the value of fNIRs for detection…
To investigate whether hyperthermia induces HR-deficiency in cervical tumors and as a feasibility study, secondly to investigate whether it is possible to detect circulating tumor cells before and after hyperthermia.
The Aptus Endosystems STAPLE International Post-Market Registry is intended to expand the clinical knowledge base by including 'real world' subjects. As an active means of data collection, the Registry will serve to address post-production…
The purpose of this investigation is to evaluate the ESPOIR PV in comparison to current valve substitutes within a large prospective multicentre surveillance at 8 leading European Centres for Congenital Cardiothoracic Surgery regarding re-operation…
The objectives of this pilot study are to test the feasibility, acceptability and implementation fidelity of the telemonitoring intervention; to test the study procedures for effect evaluation; and to determine the likelihood of achieving desired…
Primary Objective: To compare peri-implant hard and soft tissue changes as measured on standardized intraoral radiographs and direct digital intraoral scans between the group of single final and and the group of multiple repeated abutment dis/re-…
The primary objective is to compare GLP-1R-imaging to standard imaging techniques now used in pre-operative imaging of patients with AHH. All patients will undergo the standard imaging procedures of the specific centre and in addition we will…
The primary objective of this trial is to assess the effectiveness of IG-SBRT in patients with medically inoperable early stage, centrally located NSCLC and in those who are not willing to undergo surgical treatment.The primary measure of…
Primary Objective: Evaluate the functional integrity of the nociceptive system after percutaneous cervical chordotomy using Laser Evoked Potentials Secondary Objective(s): change in opioid consumption after percutaneous cervical chordotomy using a…
To investigate whether two newly developed, potato based LOPG drinks with a different osmolarity and volume taken before exercise, differently affect gastric distress after both a short and long term exercise, running performance, and the rate of…
The main objective of this study is to investigate whether adolescents with ASD, compared to healthy controls, show difficulties in generating and updating predictions about an unfolding action sequence. Using Eye-tracking (ET) and…
The aim of this study is to determine the effectiveness of the treatment (breast reconstruction) from the perspective of the patient's. By examining the results, the impact on the well-being and satisfaction, we will be able to customize the…
To examine the protective effects of a single session of high frequency rTMS over the left dorsolateral prefrontal cortex on negative mood and motivated attention.
Primary objective:To assess the feasibility of KD in patients with glioblastoma multiforme during standard treatment.Secundary objectives:- To determine number of patients not being able to start protocol treatment (i.e. not able to reach ketosis,…
This study aims to investigate the effect of switching from Atripla® to Eviplera® on neurocognitive performances (neurocognitive testing) and imaging (functional MRI scanning) in virologically suppressed HIV-infected patients and stable on atripla.
To elucidate the molecular mechanisms underlying renal disease that lead to chronic kidney disease. To validate pathogenic variations in functional in vivo models.