4808 results
Laparoscopic gastrectomy will result in a lower post-operative burden by means of shorter post-operative hospital stay
The hypothesis of this study is that dosing everolimus 5mg twice daily(BID) instead of 10 mg once daily (QD) decreases the incidence of side effects, as a result of a lower Cmax while maintaining Cmin and AUC.
After epilepsy surgery an improvement of the sleep quality and structure can be expected as result of the disappearance or decrease of the daytime and or nocturnal seizures and the reduction of the amount of medication. After implantation of vagus…
Oral ondansetron reduces the proportion of referred children to a (paediatric) emergency department when added to oral rehydration therapy compared to oral rehydration therapy alone.
Recurrent ventricular tachycardia (VT) is an important cause for mortality and morbidity in patients with left dominant non ischemic cardiomyopathy (NICM). Since implantable cardioverter defibrillators (ICDs) may only terminate and not prevent…
An expectative management ('watchful waiting') is not inferior regarding the composite of mortality and/or necrotising enterocolitis and/or bronchopulmonary dysplasia in comparison with an early treatment regime in preterm infants with a…
-Low dose radiotherapy has positive effects on pain and functioning in osteoarthritis of the hand and knee -Low dose radiotherapy is effective on reducing inflammatory signs of osteoarthritis of the hand and knee
In this RCT we investigate the effects of two school-based physical activity interventions (aerobic exercises versus coordinative exercises) in primary school children on executive functions and academic achievement. We hypothesize that both aerobic…
Two hours of end-ischemic hypothermic oxygenated perfusion via both the hepatic artery and the portal vein is feasible and safe in resuscitating liver grafts procured from donation after circulatory death donors.
Circulating tumour cells can help to diagnose Non small cell lung cancer (NSCLC), making the painful and invasive procedure of a lungbiopsy and bronchoscopy unnecesary. However, for this, we need to harvest higher amounts of CTC's and in more…
1. There are differences of thermoregulatory behavior and thermo-physiology between healthy lean and obese subjects. 2. Healthy lean and obese individuals can be classified based on individual thermal preference, which is a result of distinct…
1. Gatekeeper training is effective in enhancing relevant skills 2. Gatekeeper training will diminish rates of (attempted) suicides at regional level 3. The intervention is cost-effective relative to routine medical care
Primary objective: The primary objective is to answer the question: How do COPD patients experience intensive care unit admission because of exacerbation and what is the impact on their quality of life. This study aims to understand the perspective…
Painreduction for 67% of patients with a locally advanced or local recurrent pancreatic carcinoma through a short radiotherapy scheme (single arm phase 2 study)
Vitamin D supplementation reduces the incidence of delayed union in fracture patients with a vitamin D insufficiency, compared to placebo.
We hypothesize that patients with a HER2-negative primary tumor but with at least one HER2-positive CTC benefit from HER2 targeted treatment with trastuzumab
Several reasons for clozapine discontinuation are known, but the current evidence identifying patients who are at risk of discontinuation of clozapine is small and not always consistent. Also cultural differences may question if international…
Our primary outcome is to change knowledge, attitude and managing skills of prison staff. We hypothesis that the elearning module will contribute to improve knowledge, attitude and skills
The hypothesis is that minimal invasive surgical ablation through video assisted thoracoscopic surgey as a primary treatment in patients suffering from (longstanding) persistent atrial fibrillation is superior to transvenous catheter ablation
1. Participants in the CBM training condition have weaker smoking related cognitive biases than those in the placebo condition 2. Improvement in smoking cessation outcomes in participants in the CBM training condition compared to those in the…