740 results
Primary Objectives:* To compare overall survival (OS) of patients who receive NKTR-102given once every 21 days (q21d) to patients who receive Treatment ofPhysician*s Choice (TPC) selected from the following list of seven singleagentintravenous…
Clinical evaluation of dried blood spot (DBS) assay, by determining the ratio between DBS and serum levels of tamoxifen and endoxifen and to investigate if patients can obtain useful DBS at home.
The primary study objective is to assess the hypoallergenicity of an extensively hydroloyzed whey protein infant formula in children with cow's milk allergy.The second study objective is to assess the long-term effects on growth and tolerance…
Choosing the most suitable laboratory test and setting up a gold standard test to measure dabigatran. Additionally, determining maximal and minimal concentrations of the drug.
To study the effectiveness of gut-directed hypnotherapy in the treatment of IBS-like symptoms in patients with inflammatory bowel disease.
Optimalisation of the perfusion protocol for vestibular schwannoma.
The aim of this study is to evaluate the influence of extreme fixed wrist flexion and ulnar deviation due to spasticity on bone shapes of the wrist bones. We want to compare CT scan-based three-dimensional reconstructions of the spastic wrist to the…
To identify the brain and behavioral mechanisms via which oxytocin modulates communicative behavior.
An online testing approach to assess cognitive problems associated with cancer and cancer treatment.
The aim of the proposed project is to develop a user-friendly and standardized online neuropsychological test battery. It will be a concise test, measuring those domains which have proven to be most sensitive to the adverse effects of chemo- and…
The purpose of this study is to collect blood from accepted and deferred donors so that the necessary measurements can be made in a uniform way and distortion of the results can be prevented or corrected.
In this study we want to investigate if the muscle-relaxation time (muscle-RT), calculated from force profiles obtained with two different experimental methods (1) voluntary handgrip- and (2) peripheral nerve stimulation myometry, is a reliable and…
1. Measurement of the 24-hour glycemic profile in response to acute submaximal hypoxic and hyperoxic exercise in order to determine its effectiveness and select the most efficient method in reducing post-exercise hyperglycemia prevalence in…
Primary objectivesTo evaluate the effect of the CYP1A2 inhibitor, fluvoxamine, on steady state pharmacokinetics of TKI258 in patients with advanced solid tumors, excluding breast cancerSecondary objectives• To characterize the safety and…
To Establish the usefulness of MRI for assessment of the rotator cuff in patients with an Affinis short prosthesis implanted in the shoulder.
The primary objective is to test the hypothesis that, after at least 15 weeks of daily administration (4 for titration, 7 of relatively stable dose, 4 at fixed doses; Study Period II), risperidone given orally in a dose of 0.25 - 3.0 mg/d depending…
The development of an electrophysiological measuring method to describe the temporal processing of the hearing system, using the auditory steady state response.
Do patients with (recent onset, medicated) psychotic disorder (PDM), in persons at ultra high risk for later psychosis (UHR), in patients with schizophrenia who do not use anti-psychotics anymore (PDUM) report higher levels of trait anxiety (…
Primary Objective: 1. Will an exposure to oxygen with a PO2 = 190 kPa lead to changes primarily in DLno compared to DLco?Secondary Objectives: 1. After an exposure to oxygen with a PO2 = 190 kPa for one hour, are the changes primarily located in the…
The main objective is to develop an objective symptom profile of chronic neck pain patients which addresses more facets of the health problem, including sensorimotor dysfunction. The first stage is the establishment of an objective quantification of…
The objective of the study is mapping and assessing of the effects of filaggrin mutation on atopic eczema and other atopic diseases together with serological parameters.