2511 results
We hypothesize that depletion of carnitine occurs during infusion of oxaliplatin, due to increased renal loss. This secondary carnitine deficiency may contribute to the development of CIPN.
We hypothesise that the diet over time has become healthier and more sustainable. Our current study was set up to (1) identify the differences in food consumption and nutritional quality over the course of 20 years in the Netherlands using the…
It is hypothesised that compared to waiting list control condition, participants in the intervention improve their diet and physical activity on the short (6 months after baseline) and long-term (12 months after baseline; when the participant…
The effectiveness of an indicated indicated depression and anxiety prevention program ('Een Sprong Vooruit') will be tested in a Dutch sample of adolescents (aged 11-15) with high familial risk. It is expected that the adolescents who…
Our hypothesis is that piperacillin/tazobactam, ciprofloxacin, co-trimoxazole and doxycycline are able to penetrate hepatic cysts.
The study of determinants of cardiovascular disease (CVD) is important because it provides insight in risks and opportunities to reduce the burden of CVD. A major gap in our current knowledge about CVD lies in the way we measure these determinants,…
Het doel van de studie is om op de consultatiebureaus in de regio Kennemerland de haalbaarheid, kosten-effectiviteit en acceptatie van vroege opsporing naar coeliakie (door middel van case finding) bij kinderen tussen de 12 maanden en 4 jaar te…
It is hypothesized that both positive verbal suggestions regarding an inert substance and a positive imagery exercise result in a lower sensitivity to physical sensations (pain, itch, and fatigue) than neutral verbal suggestions and/or neutral…
Changing the context in which individuals make lifestyle choices has a sustained impact on the dietary intake and cardiometabolic health.
1. The intervention is effective in reducing eating disorder symptoms; 2. There is an incremental effect of intensive/frequent support from a coach in terms of reducing ED symptoms.
The constantly increasing number of aorto-iliac lesions in patients with end-stage renal disease (ESRD) seems to be the result of three main factors: increased recipient age, frequent atherosclerosis accompanying with end-stage renal disease and…
1. A multidimensional lifestyle intervention, including aspects of increased awareness, motivation, self-management, diet, exercise, and a supportive environment, improves or prevents deterioration of the cardiometabolic risk factors of SMI…
Submucosal irrigation with the Gum Irrigator will reduce bleeding on probing, pocketdepts and the amount of anearobic bacteria in the non-surgical treatment of peri-implantitis.
NT-proBNP guidance during in-hospital treatment of acutely decompensated heart failure (to strive for >30% reduction) reduces readmissions and mortality and increases the number of days alive out of hospital in the first 180 days.
High viscosity PMMA bone cement reduces the occurrence of cement leakage comprared to low viscosity PMMA bone cement.
- It is hypothesized that a tailored, outreaching and systemic intervention promotes medication adherence - It is hypothesized that a tailored, outreaching and systemic intervention has a beneficiary effect on other medical as well as psychological…
We hypothesize that administration of intravenous atropine during induction of propofol/remifentanil may have a positive effect on the hemodynamic profile and peripheral and cerebral tissue oxygenation during and after induction of anesthesia.
We hypothesize that the new AFI-III system – compared to the conventional AFI-II – enhances the distinction between early neoplasia and inflammation in BO and thus reduces the amount of false positive lesions, allowing for targeted sampling and…
We want to determine the influence and safety of probenecid on sorafenib pharmacokinetics. By inhibiting the OAT6 transporter there might be a faborable effect on Hand-foot syndrome