207 results
Intranasal administration of cobalamin can be used as an alternative for the standard intramuscular injection of cobalamin in cobalamin deficient patients.
1. Providing children with tailored non-smoking advice will prevent them from becoming a smoker; 2. Children receiving tailored non-smoking advice will have stronger cognitions in favour of non-smoking; 3. Prompting children through e-mail and SMS…
1. Certolizumab pegol, a TNF inhibitor, has recently been approved in the Netherlands for the treatment of moderate to severe rheumatoid arthritis. As efficacy in daily clinical practice can differ from the clinical (registration) trials, e.g. due…
1. The STERK-intervention will prevent early onset of anxiety and mood disorders in offspring (compared to a minimal information condition); 2. The STERK-intervention is cost-effective; 3. The effectiveness of the STERK-training will be influenced…
Xenon wil provide improved hemodynamics in patients undergoing cardioverter defribrillator implantation.
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The primary goal of this study is to determine whether it is possible to discontinue treatment with TNF blocking therapy in patients suffering from Rheumatoid Arthritis when the patient has had stable low disease activity.
In the present proposal we aim to study whether the intrauterine application of hyaloronic acid (Hyalobarrier ® Gel Endo) immediately after curettage, in patients with a recurrent curettage reduces the incidence and severity (ESGE score/…
1. Participation in an early home-based education programme compared to care as usual will significantly increase knowledge on kidney disease and treatment options, communication on renal replacement options and promote a positive attitude towards…
Chronic heart failure (CHF) is a clinical syndrome resulting from a decreased cardiac output, insufficient to maintain adequate tissue oxygenation. Eventually, inadequate tissue oxygenation will lead to pathological alterations, especially at the…
Does heated oxaliplatin reduce the acute peripheral neuropathy complaints in patient with a colorectal carcinoma.
The primary objective is to quantify the learning process of self infusion and the self infusion procedure.
Implementing the Signal-checklist and providing feed-backduring genetic counseling will: 1. Increase the number of psychosocial issues communicated during the genetic counseling session; 2. Increase the awareness of the counselor of the psychosocial…
We hypothesize that the perturbed interplay between certain constituents of the microbiota and the host is caused by invading organisms, which after crossing the epithelial barrier are capable of inciting and/or persisting an unbalanced innate…
Increased patient satisfaction, earlier mobilization with better a pain control.
1. Measure DNIC and offset analgesia in neuropathic pain patients; 2. Compare DNIC and offset analgesia in chronic pain patients with DNIC and offset analgesia in healthy volunteers; 3. Assess the effect of oral tapentadol on DNIC and offset…
The purpose of the study is to conduct a randomised controlled trial with the onlinecourse 'Voluit Leven' as an intervention to study the: 1. Cost-effectiveness in terms of reduction of psychological symptoms (mood symptoms and disorders…
We want to establish an abbreviated, multidimensional, evidence based, diagnostic personalityprotocol within the mental health services. The hypothesis is that the mutidimensional testcombination of VTCI, NEO-FFI and CISS is sufficient reliable and…
Interferons (IFNs) are a family of cytokines which have important antiviral and antiproliferative properties. They also play an important role in immunomodulation. Type I IFNs have been implicated in autoimmune diseases, including systemic lupus…
The use of the laparoscopic insertion technique will lower the proportion of malfunctioning PD-catheters.