286 results
The main objective of the present protocol is to investigate to what extent oxytocin modulates specific aspects of interpersonal approach, mimicry, and communication in healthy volunteers with varying degrees of social anxiety.Results from this…
Primary objectiveTo measure the conversion rate of mono- and disaccharides into oligosaccharides and mannitol in the digestive tract by the action of food grade micro-organisms Secondary objectivesTo measure pH of gastric and duodenal fluids at…
Aim of researchThe overall aim of this research is to contribute to a more adequate and congruent professional counselling of (intended) parents in the process of decision making on (non) disclosure of GD with their child.The specific aims are:1. to…
This study will learn us about the prevalence of asymptomatic urinary retention postpartum, as well as the natural course and complications.
The primary objective is to elucidate the question whether historic HBV viral load (in samples taken from 1989 * 1996 during pregnancy) is associated with the risk of HBV-related cirrhosis or mortality in a cohort of non-Asian individuals with…
1. To investigate the efficacy of Cogmed working memory training in reducing behavioral symptoms in children with neuropsychiatric disorders and borderline intellectual functioning.2. To investigate whether WM training improves neurocognitive…
Evaluation of the efficacy and tolerability of adding verapamil to the antiepileptic drug regimen in patients who did not become seizure free on carbamazepine.
The primary objective of this study is to assess the relation between the short term metabolic changes after start of rhGH therapy and the long term change in height SDS after one year of treatment. Secondly, we want to assess the effects of GH on…
To determine the effect of hypoglycaemia on BAT-activity.
The goal of this study is to positively influence quality of life in patients with hypothyroidism by giving them back control in their treatment. We also want to see what the placebo effect will be. And at last we want to check if patients have the…
Compare the performance of the Philips Respironics Sleep Therapy Auto System to a fixed CPAP device for the treatment of OSA and validate its event detection capabilities.
To perform a human pilot study to prove the hypothesis that a hybrid transgastric cholecystectomy is a safe procedure.
To evaluate whether healthy subjects and cocaine addicts carrying the s-variant of the 5-HTTLPR show improved reversal learning and reduced 5HTT function.
The primary objective of this study is to evaluate overall survival (OS) in the intent-to-treat (ITT) subject population defined by this protocol.Key secondary objectives are to evaluate OS in the epidermal growth factor receptor (EGFR) wild type…
The primary objective of this study is to determine if TVTO-PA is non-inferior to TVT-O in the objective cure of women with Stress Urinary Incontinence (SUI).The secondary objectives of the study are to evaluate changes in incontinence-specific…
To evaluate the efficacy and safety of nilotinib in spondyloarthritis
The aim of this study is to compare the early post-operative migration as measured by Roentgen Stereophotogrammetric Analysis (RSA) of the cemented tibial component with the uncemented porous coated tibia component.
Primary objective: To determine if a single administration of SRT2379, at multiple dose levels, attenuates the inflammatory response in normal healthy male subjects after exposure to low-dose endotoxin (LPS)Secondary objectives: (1) To determine…
To evaluate the efficacy and safety of extended release (ER) Niacin/Laropiprant when added to ongoing lipid-modifying therapy in patients with primary hypercholesterolemia or mixed dyslipidemia.
The objective of this study is to gain insight in HIV infected children in the AMC in:.- the prevalence and clinical signs of livertoxicity - an association between the different compounds of combination anti-retroviral therapy (cART) and…