4614 results
To confirm the safety of the Articulinx ICC by evaluating device- and procedure relates adverse events.
To determine the effectiveness and, subsequently, the cost-effectiveness of a endoscopic transluminal step-up approach (ETD & ETN) versus a surgical step-up approach (PCD & VARD ,if not possible laparotomy) to improve clinical…
Imaging disease activity in patients with Graves' orbitopathy using [18F]-FDG-PET/CT - a pilot study
To determine whether 18FGD-PET/CT imaging is able to show difference in [18F]-FDG uptake in orbital tissue between patients with active and inactive GO.
Phase 1: Investigate a possible suppressing effect of prophylactic paracetamol use in adults on the response of the hepatitis B vaccination. Phase 2: Study the association between timing of the use of paracetamol during hepatitis B vaccination and…
• To investigate the magnitude and time course of platelet reactivity and platelet activation in patients with a STEMI undergoing primary percutaneous coronary intervention (pPCI).• To investigate the magnitude and time course of thrombin generation…
In the present proposal, we aim to assess the cost-effectiveness of the use of CGMS in diabetic pregnancies.
The objective of the trial is to confirm efficacy and a favorable benefit-risk ratio for BIBF 1120 in the treatment of IPF at the dose of 150 mg bid compared to placebo.
Based on the data available, Anamorelin HCl produces an increase in total body weight and Lean Body Mass in patients with advanced cancer, and specifically in patients with NSCLC, in addition to increasing muscle strength and improving quality of…
The aim of this study is to determine the accumulation of nadroparin used in renal insufficient patients with VTE, by measuring anti-Xa levels.
To study HPA axis regulation and sympathetic nervous system activity in survivors of childhood ALL during relaxation and during stress.
To assess if a continued rehabilitation program in the first six weeks post-surgery for patients following a first time is morecost-effective as compared to no further treatment after discharge from the hospital an economic evaluation alongside…
Phase 1Primary objective- To determine the maximum tolerated dose (MTD) and recommended phase 2 dose level (RDL) of lenalidomide administered during 21 days of a 4 week cycle, combined with continuous cyclophosphamide and prednisone. See paragraph…
OBJECTIVESThe objective is to quantify the cost-effectiveness and efficacy of formally applying the guideline evaluating the risk-benefit ratio of the duration of anticoagulant therapy (VKA treatment) by a previously developed VTE recurrence…
The primary objective of this randomized trial is to assess the beneficial effects of early administration of 5 mg Metoprolol intravenously before reperfusion on infarct size in patients with ST elevation myocardial infarction who are planned to…
Primary objectives:The primary objectives of this trial are:• To show PK similarity of BI 695500 to MabThera® and Rituxan® and of Rituxan® to MabThera® (three-way PK similarity).• To establish statistical equivalence of efficacy of BI 695500 and…
The primary goal of the study is to examine whether fluctuations in cognitive functioning can be measured in daily life. Another goal is to study which factors influence cognitive functioning in daily life. Finally, it will be examined whether…
To assess whether preoperative radiotherapy, as an adjunct to curative-intent surgery, improves the abdominal local recurrence-free survival.
Can small buccal bony dehiscences (< 4 mm) of non-submerged dental implants, seen at initial placement, be successfully reconstructed using the guided bone regeneration (GBR) technique with a mixture of Straumann bone ceramic and locally…
Comparative effectiveness research to determine cost-effectiveness of an existing healthcare policy, i.e. treatment with low molecular weight heparin (LMWH) after knee arthroscopy and lower leg plaster cast immobilization following surgical or…
The objective of the present study is to investigate the course of psychosocial functioning in stroke patients and their partners, during the first 2 years post-stroke, to investigate factors predicting psychosocial functioning in stroke patients…