386 results
To investigate whether high resolution multi-site epicardial mapping of the atria in patients with structural heart disease undergoing cardiac surgery can identify patients at risk for developing early post-operative atrial fibrillation. The…
* To study the relationship between inflammation on MRI and syndesmophyte formation with very detailedimaging methods: radiography, computed tomography (CT), 3 and 7 Tesla MRI. * To examine the time order of pathologic changes like inflammation,…
Proof of principle of imaging the polyamine concentration with 7 Tesla 1H-MR spectroscopic imaging in patients with prostate cancer
The principal aim of this project is to identify genetic biomarkers involved in susceptibility for drug-induced liver injury in a set of candidate genes (genes relevant to metabolism of drugs and immune system genes).The results of this study will…
To study the quantitative and qualitative relationship between a heat stimulus and the vasomotor response in healthy subjects and to determine the feasibility of this measurement setup for patients.
The aim of this project is to assess whether 4D-CTA can generate 3D cranial image data sets with sufficient spatial and temporal resolution to enable its use as a diagnostic tool in cerebrovascular pathology and physiology such as arteriovenous…
Part I of the study: I) to determine if one or a batch of aging marker(s) is/are associated with the presence of objectively diagnosed COPD related co-morbidity (muscle wasting, osteoporosis, cardiovascular risk, glucose intolerance, renal failure,…
1. Evaluation of gene-expression profiles of endometria of PCOS women compared to normal ovulatory women2. Identify genes and pathways which contribute to a high rate of miscarriages of PCOS women3. Identify genes and pathways related to the high…
Primary Objective: To study the arginine-NO metabolism during fracture healing and dysfunctional fracture healingSecondary Objective(s): To investigate if differences or decreased arginine and NO concentrations in bone healing form a prognostic…
Primary goal of this study:1) To determin the percentage of structural damage caused by an ankle inversion trauma. 2) Investigate to which patient characteristics, anamnestic characteristics, physical examination and structural characteristics…
The objective of the study is to determine the effectivity of this consolidation treatment, as well as the conversion rate of PR to CR in patients in PR before consolidation and the effect on the immunological recovery.
The main of objectives are to study the effect of the start of dialysis treatment (hemodialysis and peritoneal transplantation), on selected cardiovascular, nutritional parameters as well as physical activity. Secondly, a differentiation will be…
1. To construct a Dutch multicenter prospective biorepository for validation of biomarker and imaging products.2. To provide a Medical Technology Assessment (MTA) of newly developed biomarkers, contrast enhanced ultrasound and multimodality MR Iin…
The main objective of this prospective population-based study of patients with proximal SMA in the Netherlands is to register SMA patients in the Netherlands in a socalled SMA-database to study prevalence and severity of SMA types 1-4, to perform…
The purpose of this pilot study is twofold: - evaluation of the tumour movement and regression during and short after long course pre-operative therapy for locally advanced rectal cancer in order to develop an integrated or sequential dose…
1) identifying new predictors of ST, in particular of late and very late ST and drug eluting stent thrombosis2) to observe clinical outcome after an episode of a ST
Primary objective: to compare glucose profiles collected by CGM on days with and without haemodialysis in a group of insulin treated diabetic patients who are on regular hemodialysis treatment. Secondary objectives: o assessment of frequency and…
1. We will recruit 30 probands who meet DSM-IV inclusion criteria for a primary psychotic disorder or mood disorder with psychotic features: schizophrenia, schizoaffective disorder, delusional disorder, bipolar I disorder, psychotic depression, post…
We will study the effects of the proteins of the contact activation system in thrombus formation, embolization and degradation in several coagulation assays.
The goal of this study is to perform an analysis of the ability of the different combinations of MRI technique/stimulation delivery to measure the cerebrovascular reactivity. In this study only the following stimulations will be used for the…