2933 results
We hypothesize that depletion of carnitine occurs during infusion of oxaliplatin, due to increased renal loss. This secondary carnitine deficiency may contribute to the development of CIPN.
The null hypothesis of the primary outcome measure is that there will be no significant differences in DASH scores 6 months after surgery between patients who underwent plate fixation or intramedullary fixation with a TEN. The alternate hypothesis…
We hypothesise that the diet over time has become healthier and more sustainable. Our current study was set up to (1) identify the differences in food consumption and nutritional quality over the course of 20 years in the Netherlands using the…
It is hypothesised that compared to waiting list control condition, participants in the intervention improve their diet and physical activity on the short (6 months after baseline) and long-term (12 months after baseline; when the participant…
Our hypothesis is that piperacillin/tazobactam, ciprofloxacin, co-trimoxazole and doxycycline are able to penetrate hepatic cysts.
The study of determinants of cardiovascular disease (CVD) is important because it provides insight in risks and opportunities to reduce the burden of CVD. A major gap in our current knowledge about CVD lies in the way we measure these determinants,…
Het doel van de studie is om op de consultatiebureaus in de regio Kennemerland de haalbaarheid, kosten-effectiviteit en acceptatie van vroege opsporing naar coeliakie (door middel van case finding) bij kinderen tussen de 12 maanden en 4 jaar te…
Changing the context in which individuals make lifestyle choices has a sustained impact on the dietary intake and cardiometabolic health.
The diagnostic triage will be a simple and feasible way to improve the diagnosis and treatment of frail elderly with exercise induced dyspnoea and/or reduced excersie tolerance.
The constantly increasing number of aorto-iliac lesions in patients with end-stage renal disease (ESRD) seems to be the result of three main factors: increased recipient age, frequent atherosclerosis accompanying with end-stage renal disease and…
Submucosal irrigation with the Gum Irrigator will reduce bleeding on probing, pocketdepts and the amount of anearobic bacteria in the non-surgical treatment of peri-implantitis.
Subacromial disorders are considered to be the most common pathology affecting the shoulder. The optimal therapy for shoulder pain (SP) in primary care is yet unknown, since clinical history and physical examination do not provide decisive evidence…
We expect that parents involved in the program (as compared to controls) will be more involved in high qualitative communication on alcohol topics, have more confidence in discussing alcohol matters and greater efficacy to prevent their children…
- It is hypothesized that a tailored, outreaching and systemic intervention promotes medication adherence - It is hypothesized that a tailored, outreaching and systemic intervention has a beneficiary effect on other medical as well as psychological…
We want to determine the influence and safety of probenecid on sorafenib pharmacokinetics. By inhibiting the OAT6 transporter there might be a faborable effect on Hand-foot syndrome
(Experimental) participants who receive information about the availability and use of mindfulness-apps after an MBSR course: (1) report higher frequency of mindfulness practice, (2) report higher mindfulness, lower general psychopathology, and…
To compare the resection speed of two different devices for removal of polyps (≥8mm - ≤20 mm) in terms of efficiency and complications.
We hypothesize that the associations between biopsychosocial factors and post-TBI sleep complaints and fatigue change over time., i.e., that the associations with biological factors are strongest in the first six months and then decline, whereas the…
PMS increases the chance of problematic use of psychoactive substances. In case of problematic use of psychoactive substances the prevalence of PMS is higher than in case of non problematic use.
Patients with Alzheimer's disease have a significantly reduced function of the visual path compared to healthy people.